STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Sec61a2Protein transport protein Sec61 subunit alpha isoform 2. (442 aa)    
Predicted Functional Partners:
RPL3
60S ribosomal protein L3; Belongs to the universal ribosomal protein uL3 family.
  
 
 0.999
rpl-11.1
60S ribosomal protein L11; Belongs to the universal ribosomal protein uL5 family.
  
 
 0.999
rpl-23
60S ribosomal protein L23; Belongs to the universal ribosomal protein uL14 family.
  
 
 0.999
RPN1
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1; Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol- pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the en [...]
   
 0.999
rpl-7
60S ribosomal protein L7.
  
 
 0.999
SEC61B
Protein transport protein Sec61 subunit beta; Necessary for protein translocation in the endoplasmic reticulum.
   
 0.999
fau
40S ribosomal protein S30; Belongs to the eukaryotic ribosomal protein eS30 family.
    
 
 0.999
rpl-5
60S ribosomal protein L5.
 
 
 0.999
Rpl23a
60S ribosomal protein L23a; Belongs to the universal ribosomal protein uL23 family.
  
 
 0.999
Rpl35
60S ribosomal protein L35.
  
 
 0.999
Your Current Organism:
Toxocara canis
NCBI taxonomy Id: 6265
Other names: T. canis, dog roundworm
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.