STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KLHL10Kelch-like protein 10. (629 aa)    
Predicted Functional Partners:
CUL1
Cullin-1; Belongs to the cullin family.
    
 0.998
CUL3
Cullin-3; Belongs to the cullin family.
    
 0.998
RNF7
RING-box protein 2.
    
 0.977
Roc1a
RING-box protein 1A.
    
 0.977
ubc-12
Nedd8-conjugating enzyme ubc-12; Belongs to the ubiquitin-conjugating enzyme family.
    
 0.951
ned-8
Nedd8.
    
 0.942
ned-8-2
Nedd8.
    
 0.942
ula-1
Nedd8-activating enzyme E1 regulatory subunit.
     
 0.940
DCUN1D1
Defective in cullin neddylation protein; Neddylation of cullins play an essential role in the regulation of SCF-type complexes activity.
   
 0.930
uba-3
Nedd8-activating enzyme E1 catalytic subunit.
     
 0.930
Your Current Organism:
Toxocara canis
NCBI taxonomy Id: 6265
Other names: T. canis, dog roundworm
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.