STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DccNetrin receptor DCC. (314 aa)    
Predicted Functional Partners:
unc-6
Netrin unc-6.
    
 0.979
Appl2
DCC-interacting protein 13-beta.
    
  0.945
Tcan_05651
PID domain-containing protein.
    
  0.945
Rgmb
RGM domain family member B.
   
 0.938
unc-5
Netrin receptor unc-5.
    
 0.883
ptk2
Focal adhesion kinase 1.
   
 0.878
ced-3
Cell death protein 3; Belongs to the peptidase C14A family.
    
  0.804
Tgfbr1
Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.
    
 0.780
otk-2
Tyrosine-protein kinase-like otk.
   
 0.772
NCK2
Cytoplasmic protein NCK2.
    
 0.760
Your Current Organism:
Toxocara canis
NCBI taxonomy Id: 6265
Other names: T. canis, dog roundworm
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.