STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Tcan_01969RING-type domain-containing protein. (116 aa)    
Predicted Functional Partners:
gei-7
Bifunctional glyoxylate cycle protein.
  
 0.967
cts-1
Citrate synthase; Belongs to the citrate synthase family.
  
 0.953
cts-1-2
Citrate synthase; Belongs to the citrate synthase family.
  
 0.953
sdhb-1
Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial; Iron-sulfur protein (IP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q).
  
 0.952
Got2
Aspartate aminotransferase.
   
 0.932
GOT2
Aspartate aminotransferase, mitochondrial.
   
 0.932
C05G5.4
Succinate--CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and specificity for either ATP or GTP is provided by different beta subunits.
  
 0.931
DLD
Dihydrolipoyl dehydrogenase, mitochondrial.
  
 0.930
T01C8.5
Aspartate aminotransferase.
   
 0.924
T20H4.5
Putative NADH dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrial.
  
 0.918
Your Current Organism:
Toxocara canis
NCBI taxonomy Id: 6265
Other names: T. canis, dog roundworm
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