STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ubr-1E3 ubiquitin-protein ligase; Ubiquitin ligase protein which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N- terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation. (2104 aa)    
Predicted Functional Partners:
TRIP12
E3 ubiquitin-protein ligase TRIP12.
   
 0.995
ubc-1
Ubiquitin-conjugating enzyme E2 1; Belongs to the ubiquitin-conjugating enzyme family.
    
 
 0.807
Tcan_17505
Uncharacterized protein.
    
 
 0.807
Tcan_06713
Uncharacterized protein.
    
 
 0.807
RpS27A
Ubiquitin-40S ribosomal protein S27a.
   
 0.783
ubq-1
Polyubiquitin-A.
   
 0.748
ubq-1-2
Polyubiquitin-A.
   
 0.748
ubq-1-3
Polyubiquitin-A.
   
 0.748
Tcan_14801
Uncharacterized protein.
    
 
 0.737
MEIS3
Homeobox protein Meis3.
    
 
 0.708
Your Current Organism:
Toxocara canis
NCBI taxonomy Id: 6265
Other names: T. canis, dog roundworm
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