STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Chac2Gamma-glutamylcyclotransferase; Catalyzes the cleavage of glutathione into 5-oxo-L-proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides; Belongs to the gamma-glutamylcyclotransferase family. (202 aa)    
Predicted Functional Partners:
OPLAH
5-oxoprolinase.
     
 0.847
Gss
Glutathione synthetase.
     
 0.829
chac1
Gamma-glutamylcyclotransferase; Catalyzes the cleavage of glutathione into 5-oxo-L-proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides; Belongs to the gamma-glutamylcyclotransferase family.
  
  
 
0.827
cth-2
Putative cystathionine gamma-lyase 2.
   
 
 0.824
Ggct
Gamma-glutamylcyclotransferase.
     
 0.824
F17C11.9
Putative elongation factor 1-gamma.
     
 0.816
TXNDC12
Thioredoxin domain-containing protein 12.
    
 0.810
gpx-3
Glutathione peroxidase; Belongs to the glutathione peroxidase family.
    
 0.809
Tcan_14390
1-Cys peroxiredoxin.
    
 0.808
gst-36
Putative glutathione S-transferase gst-36; Belongs to the GST superfamily.
     
 0.807
Your Current Organism:
Toxocara canis
NCBI taxonomy Id: 6265
Other names: T. canis, dog roundworm
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.