STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PLCG1Phosphoinositide phospholipase C. (1710 aa)    
Predicted Functional Partners:
let-23
Receptor protein-tyrosine kinase.
    
 0.984
otk-2
Tyrosine-protein kinase-like otk.
    
 0.951
Ephb1
Ephrin type-B receptor 1.
    
 0.940
vav-1
Protein vav-1.
   
 0.934
sem-5
Sex muscle abnormal protein 5.
    
0.921
sem-5-2
Sex muscle abnormal protein 5.
    
 0.921
drk
Protein E(Sev)2B.
    
0.921
ITPR1
Inositol 1,4,5-trisphosphate receptor type 1.
     
 0.918
Itpka
Kinase; Belongs to the inositol phosphokinase (IPK) family.
     
 0.917
age-1
Phosphatidylinositol 3-kinase age-1; Belongs to the PI3/PI4-kinase family.
    
 0.910
Your Current Organism:
Toxocara canis
NCBI taxonomy Id: 6265
Other names: T. canis, dog roundworm
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.