STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
aex-3MAP kinase-activating death domain protein. (1377 aa)    
Predicted Functional Partners:
rab-3
Ras-related protein Rab-3.
    
 0.871
Rab27a
Ras-related protein Rab-27A.
     
 0.860
GDI1
Rab GDP dissociation inhibitor alpha.
     
 0.699
Plekhg6
Pleckstrin homology domain-containing family G member 6.
    
 0.696
Tcan_12441
Uncharacterized protein.
    
 0.696
Rep
Rab proteins geranylgeranyltransferase component A.
     
 0.675
PLEKHG7
Pleckstrin homology domain-containing family G member 7.
    
 0.674
Rab35
Ras-related protein Rab-35.
      
 0.600
RAB3GAP2
Rab3 GTPase-activating protein non-catalytic subunit.
      
 0.596
dennd1a
DENN domain-containing protein 1A.
    
 
0.541
Your Current Organism:
Toxocara canis
NCBI taxonomy Id: 6265
Other names: T. canis, dog roundworm
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.