STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
sh3rf1E3 ubiquitin-protein ligase SH3RF1. (444 aa)    
Predicted Functional Partners:
RpS27A
Ubiquitin-40S ribosomal protein S27a.
    
 0.719
ced-3
Cell death protein 3; Belongs to the peptidase C14A family.
    
 0.660
F43C1.1
Protein phosphatase PHLPP-like protein.
    
 0.657
fau
40S ribosomal protein S30; Belongs to the eukaryotic ribosomal protein eS30 family.
    
 0.650
ubq-1
Polyubiquitin-A.
    
 0.631
ubq-1-2
Polyubiquitin-A.
    
 0.631
ubq-1-3
Polyubiquitin-A.
    
 0.631
Ube2l3
Ubiquitin-conjugating enzyme E2 L3; Belongs to the ubiquitin-conjugating enzyme family.
    
 0.629
Ube2l3-2
Ubiquitin-conjugating enzyme E2 L3.
    
 0.629
otk-2
Tyrosine-protein kinase-like otk.
    
 0.618
Your Current Organism:
Toxocara canis
NCBI taxonomy Id: 6265
Other names: T. canis, dog roundworm
Server load: low (28%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.