STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SrmSpermidine synthase; Belongs to the spermidine/spermine synthase family. (355 aa)    
Predicted Functional Partners:
AASS-2
Alpha-aminoadipic semialdehyde synthase, mitochondrial.
   
 0.975
rocF
Arginase; Belongs to the arginase family.
  
 
 0.950
rocF-2
Arginase; Belongs to the arginase family.
  
 
 0.950
smd-1
S-adenosylmethionine decarboxylase proenzyme.
    
 0.941
odc-1
Ornithine decarboxylase; Belongs to the Orn/Lys/Arg decarboxylase class-II family.
  
 0.938
odc-1-2
Ornithine decarboxylase; Belongs to the Orn/Lys/Arg decarboxylase class-II family.
  
 0.938
Tcan_03781
S-methyl-5'-thioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates.
  
 
 0.935
C16A3.10
Putative ornithine aminotransferase, mitochondrial; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
    
 0.920
Smox
Spermine oxidase.
     
 0.919
nft-1
Bis(5'-adenosyl)-triphosphatase.
  
 
 0.914
Your Current Organism:
Toxocara canis
NCBI taxonomy Id: 6265
Other names: T. canis, dog roundworm
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.