STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PlecPlectin. (3781 aa)    
Predicted Functional Partners:
pat-3
Integrin beta; Belongs to the integrin beta chain family.
   
 0.900
C05D9.3
Putative integrin beta-like protein C05D9.3.
   
 0.900
bar-1
Beta-catenin/armadillo-related protein 1.
    
 0.816
hmp-2
Protein humpback-2.
    
 0.816
ced-3
Cell death protein 3; Belongs to the peptidase C14A family.
   
 0.770
alpha-Spec-2
Spectrin alpha chain.
   
 0.765
alpha-Spec-3
Spectrin alpha chain.
   
0.765
alpha-Spec
Spectrin alpha chain.
   
 0.736
NCK2
Cytoplasmic protein NCK2.
    
 0.720
Eny2
Transcription and mRNA export factor ENY2; Involved in mRNA export coupled transcription activation by association with both the TREX-2 and the SAGA complexes. The transcription regulatory histone acetylation (HAT) complex SAGA is a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex, participates to a subcomplex that specifically deubiquitinates histones. The SAGA complex is recruited to specific gene promoters by activators, where it is required for transcription. The TREX-2 complex [...]
    
 0.716
Your Current Organism:
Toxocara canis
NCBI taxonomy Id: 6265
Other names: T. canis, dog roundworm
Server load: low (26%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.