CACYBP protein (Toxocara canis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

CACYBP

Calcyclin-binding protein. (288 aa)

Predicted Functional Partners:

siah-1

0.992

sconC-2

0.905

sconC

0.870

Skp1

0.870

Tcan_18108

0.870

Skp1-2

0.870

sconC-3

0.855

AHSA1

0.740

RDH14

0.628

RDH14-3

0.628

Your Current Organism:

Toxocara canis

NCBI taxonomy Id: 6265
Other names: T. canis, dog roundworm

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AHSA1	CACYBP	A0A0B2UYB5	A0A0B2V601	Activator of 90 kDa heat shock protein ATPase-like protein 1.	Calcyclin-binding protein.	0.740
CACYBP	AHSA1	A0A0B2V601	A0A0B2UYB5	Calcyclin-binding protein.	Activator of 90 kDa heat shock protein ATPase-like protein 1.	0.740
CACYBP	RDH14	A0A0B2V601	A0A0B2UWD3	Calcyclin-binding protein.	Retinol dehydrogenase 14.	0.628
CACYBP	RDH14-3	A0A0B2V601	A0A0B2VQJ2	Calcyclin-binding protein.	Retinol dehydrogenase 14.	0.628
CACYBP	Skp1	A0A0B2V601	A0A0B2UVR0	Calcyclin-binding protein.	S-phase kinase-associated protein 1; Belongs to the SKP1 family.	0.870
CACYBP	Skp1-2	A0A0B2V601	A0A0B2VAK4	Calcyclin-binding protein.	S-phase kinase-associated protein 1; Belongs to the SKP1 family.	0.870
CACYBP	Tcan_18108	A0A0B2V601	A0A0B2UXN6	Calcyclin-binding protein.	Uncharacterized protein.	0.870
CACYBP	sconC	A0A0B2V601	A0A0B2USM0	Calcyclin-binding protein.	E3 ubiquitin ligase complex SCF subunit sconC; Belongs to the SKP1 family.	0.870
CACYBP	sconC-2	A0A0B2V601	A0A0B2UY40	Calcyclin-binding protein.	E3 ubiquitin ligase complex SCF subunit sconC; Belongs to the SKP1 family.	0.905
CACYBP	sconC-3	A0A0B2V601	A0A0B2VC88	Calcyclin-binding protein.	E3 ubiquitin ligase complex SCF subunit sconC; Belongs to the SKP1 family.	0.855
CACYBP	siah-1	A0A0B2V601	A0A0B2VJ35	Calcyclin-binding protein.	E3 ubiquitin-protein ligase; E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates.	0.992
RDH14	CACYBP	A0A0B2UWD3	A0A0B2V601	Retinol dehydrogenase 14.	Calcyclin-binding protein.	0.628
RDH14-3	CACYBP	A0A0B2VQJ2	A0A0B2V601	Retinol dehydrogenase 14.	Calcyclin-binding protein.	0.628
Skp1	CACYBP	A0A0B2UVR0	A0A0B2V601	S-phase kinase-associated protein 1; Belongs to the SKP1 family.	Calcyclin-binding protein.	0.870
Skp1-2	CACYBP	A0A0B2VAK4	A0A0B2V601	S-phase kinase-associated protein 1; Belongs to the SKP1 family.	Calcyclin-binding protein.	0.870
Tcan_18108	CACYBP	A0A0B2UXN6	A0A0B2V601	Uncharacterized protein.	Calcyclin-binding protein.	0.870
sconC	CACYBP	A0A0B2USM0	A0A0B2V601	E3 ubiquitin ligase complex SCF subunit sconC; Belongs to the SKP1 family.	Calcyclin-binding protein.	0.870
sconC-2	CACYBP	A0A0B2UY40	A0A0B2V601	E3 ubiquitin ligase complex SCF subunit sconC; Belongs to the SKP1 family.	Calcyclin-binding protein.	0.905
sconC-3	CACYBP	A0A0B2VC88	A0A0B2V601	E3 ubiquitin ligase complex SCF subunit sconC; Belongs to the SKP1 family.	Calcyclin-binding protein.	0.855
siah-1	CACYBP	A0A0B2VJ35	A0A0B2V601	E3 ubiquitin-protein ligase; E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates.	Calcyclin-binding protein.	0.992