STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ire-1Serine/threonine-protein kinase/endoribonuclease ire-1. (284 aa)    
Predicted Functional Partners:
hsp-3
Heat shock 70 kDa protein C.
   
 0.964
hsp-3-2
Heat shock 70 kDa protein C; Belongs to the heat shock protein 70 family.
   
 0.964
ire-1-2
Serine/threonine-protein kinase/endoribonuclease ire-1.
 
      0.900
Map3k15
Mitogen-activated protein kinase kinase kinase 15.
   
 0.887
XBP1
X-box-binding protein 1.
    
 0.875
Traf1
TNF receptor-associated factor 1.
   
 0.873
unc-89-3
Muscle M-line assembly protein unc-89.
   
 0.872
unc-89-4
Muscle M-line assembly protein unc-89.
   
 0.872
unc-89-5
Muscle M-line assembly protein unc-89.
   
 0.872
Tcan_01821
Uncharacterized protein.
   
 0.787
Your Current Organism:
Toxocara canis
NCBI taxonomy Id: 6265
Other names: T. canis, dog roundworm
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.