pit protein (Toxocara canis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

pit

RNA helicase. (554 aa)

Predicted Functional Partners:

Tcan_14639

0.999

Tcan_12484

0.999

Tcan_03949

0.998

T07A9.9

0.998

nst-1

0.998

WDR74

0.998

K12H4.3

0.998

Tcan_05783

0.998

bms1

0.998

Y54E10A.10

0.997

Your Current Organism:

Toxocara canis

NCBI taxonomy Id: 6265
Other names: T. canis, dog roundworm

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
K12H4.3	T07A9.9	A0A0B2VDN6	A0A0B2UWM4	Ribosome biogenesis protein BRX1-like protein.	Putative nucleolar GTP-binding protein 1.	0.998
K12H4.3	Tcan_03949	A0A0B2VDN6	A0A0B2UTL6	Ribosome biogenesis protein BRX1-like protein.	Pescadillo homolog; Required for maturation of ribosomal RNAs and formation of the large ribosomal subunit; Belongs to the pescadillo family.	0.996
K12H4.3	Tcan_05783	A0A0B2VDN6	A0A0B2VZM0	Ribosome biogenesis protein BRX1-like protein.	Ribosome biogenesis protein WDR12 homolog; Required for maturation of ribosomal RNAs and formation of the large ribosomal subunit; Belongs to the WD repeat WDR12/YTM1 family.	0.998
K12H4.3	Tcan_12484	A0A0B2VDN6	A0A0B2V7N7	Ribosome biogenesis protein BRX1-like protein.	Putative RNA-binding protein.	0.999
K12H4.3	Tcan_14639	A0A0B2VDN6	A0A0B2V4A6	Ribosome biogenesis protein BRX1-like protein.	Ribosomal L1 domain-containing protein.	0.998
K12H4.3	WDR74	A0A0B2VDN6	A0A0B2VAD7	Ribosome biogenesis protein BRX1-like protein.	WD repeat-containing protein 74.	0.996
K12H4.3	Y54E10A.10	A0A0B2VDN6	A0A0B2UND6	Ribosome biogenesis protein BRX1-like protein.	Ribosome production factor 2-like protein.	0.993
K12H4.3	bms1	A0A0B2VDN6	A0A0B2W5C5	Ribosome biogenesis protein BRX1-like protein.	Ribosome biogenesis protein bms1.	0.911
K12H4.3	nst-1	A0A0B2VDN6	A0A0B2V2G5	Ribosome biogenesis protein BRX1-like protein.	Guanine nucleotide-binding protein-like 3-like protein.	0.996
K12H4.3	pit	A0A0B2VDN6	A0A0B2V663	Ribosome biogenesis protein BRX1-like protein.	RNA helicase.	0.998
T07A9.9	K12H4.3	A0A0B2UWM4	A0A0B2VDN6	Putative nucleolar GTP-binding protein 1.	Ribosome biogenesis protein BRX1-like protein.	0.998
T07A9.9	Tcan_03949	A0A0B2UWM4	A0A0B2UTL6	Putative nucleolar GTP-binding protein 1.	Pescadillo homolog; Required for maturation of ribosomal RNAs and formation of the large ribosomal subunit; Belongs to the pescadillo family.	0.999
T07A9.9	Tcan_05783	A0A0B2UWM4	A0A0B2VZM0	Putative nucleolar GTP-binding protein 1.	Ribosome biogenesis protein WDR12 homolog; Required for maturation of ribosomal RNAs and formation of the large ribosomal subunit; Belongs to the WD repeat WDR12/YTM1 family.	0.998
T07A9.9	Tcan_12484	A0A0B2UWM4	A0A0B2V7N7	Putative nucleolar GTP-binding protein 1.	Putative RNA-binding protein.	0.999
T07A9.9	Tcan_14639	A0A0B2UWM4	A0A0B2V4A6	Putative nucleolar GTP-binding protein 1.	Ribosomal L1 domain-containing protein.	0.998
T07A9.9	WDR74	A0A0B2UWM4	A0A0B2VAD7	Putative nucleolar GTP-binding protein 1.	WD repeat-containing protein 74.	0.997
T07A9.9	Y54E10A.10	A0A0B2UWM4	A0A0B2UND6	Putative nucleolar GTP-binding protein 1.	Ribosome production factor 2-like protein.	0.998
T07A9.9	bms1	A0A0B2UWM4	A0A0B2W5C5	Putative nucleolar GTP-binding protein 1.	Ribosome biogenesis protein bms1.	0.964
T07A9.9	nst-1	A0A0B2UWM4	A0A0B2V2G5	Putative nucleolar GTP-binding protein 1.	Guanine nucleotide-binding protein-like 3-like protein.	0.999
T07A9.9	pit	A0A0B2UWM4	A0A0B2V663	Putative nucleolar GTP-binding protein 1.	RNA helicase.	0.998