STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Piezo2-2Piezo-type mechanosensitive ion channel component 2. (1440 aa)    
Predicted Functional Partners:
Piezo1
Piezo-type mechanosensitive ion channel component 1.
 
     0.935
chk-2
Serine/threonine-protein kinase chk-2; Belongs to the protein kinase superfamily.
    
 0.877
mcm4-a
DNA helicase; Belongs to the MCM family.
   
 0.813
ATR
Serine/threonine-protein kinase ATR; Belongs to the PI3/PI4-kinase family.
   
 0.793
Tcan_17961
UME domain-containing protein.
   
 0.793
mcm2
DNA helicase; Belongs to the MCM family.
   
 0.778
Cdc6
Cell division control protein 6-like protein.
   
 0.763
Tcan_02836
TIMELESS-interacting protein; Plays an important role in the control of DNA replication and the maintenance of replication fork stability. Belongs to the CSM3 family.
   
 
 0.743
TIMELESS
Protein timeless-like protein.
    
 
 0.719
wdhd1
WD repeat and HMG-box DNA-binding protein 1.
   
 
 0.716
Your Current Organism:
Toxocara canis
NCBI taxonomy Id: 6265
Other names: T. canis, dog roundworm
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.