STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PIGGGPI ethanolamine phosphate transferase 2. (585 aa)    
Predicted Functional Partners:
tmed10
Transmembrane emp24 domain-containing protein 10.
    
 
 0.973
T05E11.6
GPI-anchor transamidase; Mediates GPI anchoring in the endoplasmic reticulum, by replacing a protein's C-terminal GPI attachment signal peptide with a pre-assembled GPI. During this transamidation reaction, the GPI transamidase forms a carbonyl intermediate with the substrate protein. Belongs to the peptidase C13 family.
    
 0.946
Pigt
GPI transamidase component PIG-T.
    
 0.923
Tcan_09195
GPI mannosyltransferase 2; Mannosyltransferase involved in glycosylphosphatidylinositol- anchor biosynthesis.
   
 0.846
Gpaa1
Glycosylphosphatidylinositol anchor attachment 1 protein.
   
 0.768
PIGU
Phosphatidylinositol glycan anchor biosynthesis class U protein.
   
 0.718
PIGS
GPI transamidase component PIG-S.
   
 0.705
Kdsr
3-ketodihydrosphingosine reductase; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
     
 0.695
MPPE1
Metallophosphoesterase 1.
    
 
 0.669
GANAB
Neutral alpha-glucosidase AB; Belongs to the glycosyl hydrolase 31 family.
   
  0.655
Your Current Organism:
Toxocara canis
NCBI taxonomy Id: 6265
Other names: T. canis, dog roundworm
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