STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Tcan_05029Uncharacterized protein. (104 aa)    
Predicted Functional Partners:
FANCM
Fanconi anemia group M protein.
   
 0.999
top-3
DNA topoisomerase 3.
  
 0.979
exo1
Exonuclease 1.
  
 0.976
mus81
Crossover junction endonuclease MUS81.
   
 0.959
mre-11
Double-strand break repair protein mre-11; Belongs to the MRE11/RAD32 family.
  
 0.955
rad51-a
DNA repair protein RAD51-like protein A; Belongs to the RecA family.
  
 0.942
rmi1
RecQ-mediated genome instability protein 1.
   
 0.938
rmi1-2
RecQ-mediated genome instability protein 1.
   
 0.938
Mlh1
DNA mismatch repair protein Mlh1.
  
 0.935
rpa-1
Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage.
   
 0.929
Your Current Organism:
Toxocara canis
NCBI taxonomy Id: 6265
Other names: T. canis, dog roundworm
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.