STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Tcan_07655Voltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (1931 aa)    
Predicted Functional Partners:
unc-79
Uncoordinated protein 79.
   
 0.997
CACNB2
Voltage-dependent L-type calcium channel subunit beta-2.
   
 0.963
CACNB4
Voltage-dependent L-type calcium channel subunit beta-4.
   
 0.935
unc-36
Voltage-dependent calcium channel unc-36.
   
 0.911
Cacna1h
Voltage-dependent T-type calcium channel subunit alpha-1H.
  
0.895
Wdr35
WD repeat-containing protein 35.
    
 0.884
ift122
Intraflagellar transport protein-like protein.
   
 0.877
Cacna2d2
Voltage-dependent calcium channel subunit alpha-2/delta-2.
   
 0.876
unc-36-2
Voltage-dependent calcium channel unc-36.
   
 0.873
GRAMD1B
GRAM domain-containing protein 1B.
   
 0.870
Your Current Organism:
Toxocara canis
NCBI taxonomy Id: 6265
Other names: T. canis, dog roundworm
Server load: low (10%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.