STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
der-2Derlin; May be involved in the degradation of misfolded endoplasmic reticulum (ER) luminal proteins; Belongs to the derlin family. (237 aa)    
Predicted Functional Partners:
SEL1L
Protein sel-1-like protein 1.
   
 0.996
Tcan_09072
Uncharacterized protein.
   
 0.988
AMFR
E3 ubiquitin-protein ligase AMFR.
   
 0.987
sel-11
E3 ubiquitin-protein ligase hrd-1; Belongs to the syntaxin family.
   
 0.987
Nploc4
Nuclear protein localization protein 4-like protein.
    
 
 0.987
ufd-1
Ubiquitin fusion degradation protein 1-like protein.
   
 
 0.987
Spata5
Spermatogenesis-associated protein 5; Belongs to the AAA ATPase family.
   
 0.978
cdc-48.2
Transitional endoplasmic reticulum ATPase-like protein 2; Belongs to the AAA ATPase family.
   
 0.978
Tcan_09348
ERGIC_N domain-containing protein.
   
 
 0.970
Erlec1
Endoplasmic reticulum lectin 1.
    
 0.970
Your Current Organism:
Toxocara canis
NCBI taxonomy Id: 6265
Other names: T. canis, dog roundworm
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.