STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Slx4Structure-specific endonuclease subunit SLX4. (1049 aa)    
Predicted Functional Partners:
Eprs
Bifunctional glutamate/proline--tRNA ligase.
  
 0.999
Tcan_04703
Structure-specific endonuclease subunit SLX1 homolog; Catalytic subunit of a heterodimeric structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination. Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA; Belongs to the SLX1 family.
   
 0.981
mus81
Crossover junction endonuclease MUS81.
  
 0.974
FANCM
Fanconi anemia group M protein.
  
 0.971
pet112
Glutamyl-tRNA(Gln) amidotransferase subunit B, mitochondrial; Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in the mitochondria. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln). Belongs to the GatB/GatE family. GatB subfamily.
  
 0.966
mrs-1
Methionine--tRNA ligase, cytoplasmic; Belongs to the class-I aminoacyl-tRNA synthetase family.
  
 0.962
ERCC1
DNA excision repair protein ERCC-1.
   
 0.953
Ercc4
DNA repair endonuclease XPF.
  
 0.944
Tcan_12277
Uncharacterized protein.
  
 0.944
Tcan_12018
Bifunctional glutamate/proline--tRNA ligase.
  
 0.934
Your Current Organism:
Toxocara canis
NCBI taxonomy Id: 6265
Other names: T. canis, dog roundworm
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