STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
gcy-1-14Guanylate cyclase receptor-type gcy-1. (200 aa)    
Predicted Functional Partners:
unc-89-3
Muscle M-line assembly protein unc-89.
     
 0.805
unc-89-4
Muscle M-line assembly protein unc-89.
     
 0.805
unc-89-5
Muscle M-line assembly protein unc-89.
     
 0.805
pde-5
Phosphodiesterase.
   
 0.660
Pde2a
cGMP-dependent 3',5'-cyclic phosphodiesterase.
   
 0.660
pde-4
Putative 3',5'-cyclic phosphodiesterase pde-4; Belongs to the cyclic nucleotide phosphodiesterase family.
   
 0.652
pde-4-2
Putative 3',5'-cyclic phosphodiesterase pde-4.
   
 0.652
Gnas
Guanine nucleotide-binding protein.
    
 0.627
Tcan_06578
Guanine nucleotide-binding proteinG(S) subunit alpha.
    
 0.627
Tcan_04990
Inosine triphosphate pyrophosphatase; Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) or xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family.
    
  0.567
Your Current Organism:
Toxocara canis
NCBI taxonomy Id: 6265
Other names: T. canis, dog roundworm
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.