STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
mdh1-2Malate dehydrogenase. (370 aa)    
Predicted Functional Partners:
gei-7
Bifunctional glyoxylate cycle protein.
  
 0.963
cts-1
Citrate synthase; Belongs to the citrate synthase family.
  
 0.943
cts-1-2
Citrate synthase; Belongs to the citrate synthase family.
  
 0.943
T01C8.5
Aspartate aminotransferase.
   
 0.916
GART
Trifunctional purine biosynthetic protein adenosine-3; In the C-terminal section; belongs to the GART family. In the central section; belongs to the AIR synthase family.
  
 
 0.915
Tcan_18139
Putative ATP-citrate synthase.
  
 0.906
fum-1
Putative fumarate hydratase, mitochondrial.
  
 0.890
fum-1-2
Putative fumarate hydratase, mitochondrial.
  
 0.890
mdh-2
Putative malate dehydrogenase, mitochondrial.
   
 0.885
C05G5.4
Succinate--CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and specificity for either ATP or GTP is provided by different beta subunits.
  
 0.885
Your Current Organism:
Toxocara canis
NCBI taxonomy Id: 6265
Other names: T. canis, dog roundworm
Server load: low (26%) [HD]