STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pde-3-2Putative 3',5'-cyclic phosphodiesterase pde-3. (256 aa)    
Predicted Functional Partners:
Cant1
Soluble calcium-activated nucleotidase 1.
     
 0.732
mig-23
Nucleoside-diphosphatase mig-23; Belongs to the GDA1/CD39 NTPase family.
     
 0.723
T19B4.3
Adenine phosphoribosyltransferase.
     
 0.719
pdl-1
Phosphodiesterase delta-like protein.
     
 0.711
ND42
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial.
     
 0.708
let-754
Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism. Adenylate kinase activity is critical for regulation of the phosphate utilization and the AMP de novo biosynthesis pathways.
     
 0.702
ADK1
Adenosine kinase 1.
     
 0.701
Tcan_04990
Inosine triphosphate pyrophosphatase; Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) or xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family.
     
 0.701
ADCY9
Adenylate cyclase type 9.
     
 0.686
F43C1.1
Protein phosphatase PHLPP-like protein.
     
 0.686
Your Current Organism:
Toxocara canis
NCBI taxonomy Id: 6265
Other names: T. canis, dog roundworm
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