STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CDKL1Cyclin-dependent kinase-like 1; Belongs to the protein kinase superfamily. (256 aa)    
Predicted Functional Partners:
fmr1
Fragile X mental retardation protein 1-like protein.
    
 
 0.626
slp2
Fork head domain transcription factor slp2.
      
 0.574
sir-2.1
NAD-dependent protein deacetylase sir-2.1.
    
 
 0.475
dlk-1-2
Mitogen-activated protein kinase kinase kinase dlk-1.
  
     0.456
unc-18
Putative acetylcholine regulator unc-18; Belongs to the STXBP/unc-18/SEC1 family.
      
 0.436
FER-7
Tyrosine-protein kinase Fer; Belongs to the protein kinase superfamily. Tyr protein kinase family.
  
     0.415
Tmem17b
Transmembrane protein 17B.
      
 0.410
Your Current Organism:
Toxocara canis
NCBI taxonomy Id: 6265
Other names: T. canis, dog roundworm
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.