STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
tdkThymidine kinase; KEGG: bfs:BF0583 9.6e-40 tdk; putative thymidine kinase K00857; Psort location: Cytoplasmic, score: 8.96. (116 aa)    
Predicted Functional Partners:
thyA
Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
   
 
 0.955
EEX71588.1
KEGG: bfr:BF1494 1.3e-33 cytidine deaminase K01489.
    
 0.930
dut
dUTP diphosphatase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family.
   
 
 0.920
EEX71254.1
Cytidine and deoxycytidylate deaminase zinc-binding region; KEGG: bth:BT4260 1.5e-57 deoxycytidylate deaminase K01493; Psort location: Cytoplasmic, score: 8.96.
  
 
 0.876
EEX72758.1
Phosphorylase family; KEGG: bth:BT4554 7.6e-118 purine nucleoside phosphorylase II K00757; Psort location: Cytoplasmic, score: 8.96.
     
 0.864
EEX71767.1
Purine nucleoside phosphorylase I, inosine and guanosine-specific; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.
    
  0.859
EEX72507.1
KEGG: bfs:BF0583 1.1e-13 tdk; putative thymidine kinase K00857; Psort location: Cytoplasmic, score: 8.96.
  
     0.770
EEX70471.1
Hypothetical protein; KEGG: tbd:Tbd_2668 1.1e-26 phosphoribosylaminoimidazole-succinocarboxamide (SAICAR) synthetase K01923; Psort location: CytoplasmicMembrane, score: 10.00.
      0.746
EEX71651.1
KEGG: ava:Ava_0809 1.9e-09 HAD-superfamily hydrolase, subfamily IA, variant 1 K07025.
    
  0.673
EEX71735.1
5'-nucleotidase, C-terminal domain protein; KEGG: ctc:CTC01995 1.9e-32 2',3'-cyclic-nucleotide 2'-phosphodiesterase K01119; Belongs to the 5'-nucleotidase family.
    
  0.573
Your Current Organism:
Alloprevotella tannerae
NCBI taxonomy Id: 626522
Other names: A. tannerae ATCC 51259, Alloprevotella tannerae ATCC 51259, Prevotella tannerae ATCC 51259
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