STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EEP28879.1Hypothetical protein; Psort location: Cytoplasmic, score: 8.87. (428 aa)    
Predicted Functional Partners:
EEP28878.1
Hypothetical protein; Psort location: CytoplasmicMembrane, score: 9.99.
       0.768
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
   
 
 0.760
groL
Chaperonin GroL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.
    
   0.648
rplN
Ribosomal protein L14; Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome; Belongs to the universal ribosomal protein uL14 family.
    
   0.648
pyk
Pyruvate kinase; KEGG: tte:TTE1815 1.4e-125 pykF; pyruvate kinase K00873; Psort location: Cytoplasmic, score: 8.87.
    
   0.648
EEP27823.1
FHA domain protein; KEGG: tel:tll2410 1.0e-05 adenylate cyclase K01768; Psort location: Cytoplasmic, score: 8.87.
  
 
 0.630
EEP28880.1
Hypothetical protein.
       0.568
EEP28877.1
ROK family protein; KEGG: chy:CHY_0270 1.2e-23 glcK; glucokinase K00845; Psort location: Cytoplasmic, score: 8.87.
       0.557
dprA
DNA protecting protein DprA; Psort location: Cytoplasmic, score: 8.87.
  
    0.460
EEP27263.1
Hypothetical protein; Psort location: Cytoplasmic, score: 8.87.
  
  
 0.457
Your Current Organism:
Shuttleworthia satelles
NCBI taxonomy Id: 626523
Other names: S. satelles DSM 14600, Shuttleworthia satelles DSM 14600, Shuttleworthia satelles VPI D143K-13, Shuttleworthia satelles str. DSM 14600, Shuttleworthia satelles strain DSM 14600
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.