STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pepDXaa-His dipeptidase; KEGG: cpf:CPF_2403 1.1e-100 pepD; aminoacyl-histidine dipeptidase K01270; Psort location: Cytoplasmic, score: 8.87. (482 aa)    
Predicted Functional Partners:
glyA
Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
   
 
 0.937
EEP27392.1
Aminotransferase, class I/II; KEGG: blo:BL0783 5.1e-144 probable aminotransferase K00811; Psort location: Cytoplasmic, score: 8.87.
   
  0.925
cysK
Cysteine synthase A; KEGG: bth:BT3080 3.6e-104 cysteine synthase A K01738; Psort location: Cytoplasmic, score: 8.87.
    
 0.914
EEP29122.1
Hypothetical protein; Psort location: Cytoplasmic, score: 8.87.
 
     0.871
EEP29123.1
Oligopeptide transporter, OPT family; Psort location: CytoplasmicMembrane, score: 9.99.
       0.811
EEP27615.1
Aminotransferase, class I/II; KEGG: tte:TTE2440 6.1e-125 avtA4; PLP-dependent aminotransferases K00821; Psort location: Cytoplasmic, score: 8.87.
   
  0.786
EEP29120.1
Hypothetical protein.
       0.773
guaB
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
    
 
 0.688
EEP28512.1
Peptidase, M24 family; KEGG: bfs:BF4027 3.6e-104 putative peptidase K01262; Psort location: Cytoplasmic, score: 8.87.
 
 
 0.624
nifJ
KEGG: ctc:CTC01741 0. pyruvate-flavodoxin oxidoreductase K03737.
     
 0.578
Your Current Organism:
Shuttleworthia satelles
NCBI taxonomy Id: 626523
Other names: S. satelles DSM 14600, Shuttleworthia satelles DSM 14600, Shuttleworthia satelles VPI D143K-13, Shuttleworthia satelles str. DSM 14600, Shuttleworthia satelles strain DSM 14600
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