STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
alaSalanine--tRNA ligase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain. (921 aa)    
Predicted Functional Partners:
EEP27536.1
Threonine/alanine tRNA ligase second additional domain protein; KEGG: bld:BLi02774 2.5e-41 hypothetical protein K01872; Psort location: Cytoplasmic, score: 8.87.
  
  
 
0.923
EEP28600.1
KEGG: cyb:CYB_1515 6.8e-08 tetratricopeptide repeat/protein kinase domain protein K08884; Psort location: Cytoplasmic, score: 8.87.
   
 0.897
EEP28005.1
Putative agglutinin receptor; KEGG: btl:BALH_1401 0.0077 penicillin-binding protein; Psort location: Cellwall, score: 10.00.
   
 0.894
aspS
aspartate--tRNA ligase; Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp- AMP and then transferred to the acceptor end of tRNA(Asp). Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
  
 0.861
pheT
KEGG: cno:NT01CX_1768 4.4e-186 pheT; phenylalanyl-tRNA synthetase, beta subunit K01888; Psort location: Cytoplasmic, score: 9.98.
 
 
 0.787
ileS
isoleucine--tRNA ligase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily.
  
 
 0.772
thrS
threonine--tRNA ligase; KEGG: cac:CAC2362 5.5e-147 thrS; threonyl-tRNA synthetase K01868; Psort location: Cytoplasmic, score: 10.00; Belongs to the class-II aminoacyl-tRNA synthetase family.
  
 
 0.757
leuS
leucine--tRNA ligase; KEGG: gka:GK2842 5.9e-214 leuS; leucyl-tRNA synthetase K01869; Psort location: Cytoplasmic, score: 9.98; Belongs to the class-I aminoacyl-tRNA synthetase family.
 
 
 0.739
secD
Export membrane protein SecD; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA; Belongs to the SecD/SecF family. SecD subfamily.
  
    0.733
valS
valine--tRNA ligase; Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA- dependent manner; Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
 
  
 0.713
Your Current Organism:
Shuttleworthia satelles
NCBI taxonomy Id: 626523
Other names: S. satelles DSM 14600, Shuttleworthia satelles DSM 14600, Shuttleworthia satelles VPI D143K-13, Shuttleworthia satelles str. DSM 14600, Shuttleworthia satelles strain DSM 14600
Server load: low (26%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.