node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
EEP27817.1 | cmk | GCWU000342_01811 | GCWU000342_01237 | biotin--[acetyl-CoA-carboxylase] ligase; KEGG: chy:CHY_2371 1.5e-34 birA; BirA bifunctional protein K03524:K01947; Psort location: Cytoplasmic, score: 8.87. | Cytidylate kinase; KEGG: lsl:LSL_0900 1.6e-53 cmk; cytidylate kinase K00945; Psort location: Cytoplasmic, score: 8.87. | 0.410 |
EEP27817.1 | guaB | GCWU000342_01811 | GCWU000342_00466 | biotin--[acetyl-CoA-carboxylase] ligase; KEGG: chy:CHY_2371 1.5e-34 birA; BirA bifunctional protein K03524:K01947; Psort location: Cytoplasmic, score: 8.87. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.761 |
EEP27817.1 | nadE | GCWU000342_01811 | GCWU000342_00193 | biotin--[acetyl-CoA-carboxylase] ligase; KEGG: chy:CHY_2371 1.5e-34 birA; BirA bifunctional protein K03524:K01947; Psort location: Cytoplasmic, score: 8.87. | NAD+ synthase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. | 0.855 |
EEP27817.1 | nrdR | GCWU000342_01811 | GCWU000342_00578 | biotin--[acetyl-CoA-carboxylase] ligase; KEGG: chy:CHY_2371 1.5e-34 birA; BirA bifunctional protein K03524:K01947; Psort location: Cytoplasmic, score: 8.87. | Transcriptional regulator NrdR; Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes; Belongs to the NrdR family. | 0.594 |
cmk | EEP27817.1 | GCWU000342_01237 | GCWU000342_01811 | Cytidylate kinase; KEGG: lsl:LSL_0900 1.6e-53 cmk; cytidylate kinase K00945; Psort location: Cytoplasmic, score: 8.87. | biotin--[acetyl-CoA-carboxylase] ligase; KEGG: chy:CHY_2371 1.5e-34 birA; BirA bifunctional protein K03524:K01947; Psort location: Cytoplasmic, score: 8.87. | 0.410 |
cmk | guaB | GCWU000342_01237 | GCWU000342_00466 | Cytidylate kinase; KEGG: lsl:LSL_0900 1.6e-53 cmk; cytidylate kinase K00945; Psort location: Cytoplasmic, score: 8.87. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.628 |
cmk | nrdR | GCWU000342_01237 | GCWU000342_00578 | Cytidylate kinase; KEGG: lsl:LSL_0900 1.6e-53 cmk; cytidylate kinase K00945; Psort location: Cytoplasmic, score: 8.87. | Transcriptional regulator NrdR; Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes; Belongs to the NrdR family. | 0.726 |
efp | guaB | GCWU000342_00576 | GCWU000342_00466 | Translation elongation factor P; Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.597 |
efp | nrdR | GCWU000342_00576 | GCWU000342_00578 | Translation elongation factor P; Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase. | Transcriptional regulator NrdR; Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes; Belongs to the NrdR family. | 0.425 |
efp | rpiB | GCWU000342_00576 | GCWU000342_00577 | Translation elongation factor P; Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase. | KEGG: sth:STH2337 9.0e-44 ribose 5-phosphate isomerase K01808; Psort location: Cytoplasmic, score: 8.87. | 0.409 |
efp | ychF | GCWU000342_00576 | GCWU000342_00579 | Translation elongation factor P; Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase. | GTP-binding protein YchF; ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner. | 0.511 |
ftsZ | nrdR | GCWU000342_01450 | GCWU000342_00578 | Cell division protein FtsZ; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity. | Transcriptional regulator NrdR; Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes; Belongs to the NrdR family. | 0.569 |
ftsZ | polA | GCWU000342_01450 | GCWU000342_00981 | Cell division protein FtsZ; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity. | DNA-directed DNA polymerase; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity. | 0.614 |
guaB | EEP27817.1 | GCWU000342_00466 | GCWU000342_01811 | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | biotin--[acetyl-CoA-carboxylase] ligase; KEGG: chy:CHY_2371 1.5e-34 birA; BirA bifunctional protein K03524:K01947; Psort location: Cytoplasmic, score: 8.87. | 0.761 |
guaB | cmk | GCWU000342_00466 | GCWU000342_01237 | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | Cytidylate kinase; KEGG: lsl:LSL_0900 1.6e-53 cmk; cytidylate kinase K00945; Psort location: Cytoplasmic, score: 8.87. | 0.628 |
guaB | efp | GCWU000342_00466 | GCWU000342_00576 | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | Translation elongation factor P; Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase. | 0.597 |
guaB | nadE | GCWU000342_00466 | GCWU000342_00193 | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | NAD+ synthase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. | 0.411 |
guaB | nrdR | GCWU000342_00466 | GCWU000342_00578 | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | Transcriptional regulator NrdR; Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes; Belongs to the NrdR family. | 0.559 |
guaB | polA | GCWU000342_00466 | GCWU000342_00981 | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | DNA-directed DNA polymerase; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity. | 0.631 |
guaB | ychF | GCWU000342_00466 | GCWU000342_00579 | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | GTP-binding protein YchF; ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner. | 0.678 |