STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
sdaAAKEGG: tde:TDE1506 2.8e-79 sdhA; L-serine dehydratase, iron-sulfur-dependent, alpha subunit K01752; Psort location: Cytoplasmic, score: 8.87. (299 aa)    
Predicted Functional Partners:
sdaAB
KEGG: tde:TDE1507 9.7e-47 sdhB; L-serine dehydratase, iron-sulfur-dependent, beta subunit K01752; Psort location: Cytoplasmic, score: 8.87.
 
 0.999
glyA
Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
  
 
 0.962
ilvA
KEGG: fnu:FN1411 2.2e-111 threonine dehydratase K01754.
  
 
 0.930
thrH
KEGG: hch:HCH_02661 1.6e-53 thrH; phosphoserine phosphatase/homoserine phosphotransferase bifunctional protein K01079; Psort location: Cytoplasmic, score: 8.87.
   
 
 0.923
EEP27645.1
KEGG: swo:Swol_1319 1.8e-77 homoserine dehydrogenase K00003; Psort location: Cytoplasmic, score: 8.87.
   
 
  0.919
EEP28794.1
KEGG: sfu:Sfum_2682 5.9e-67 serine O-acetyltransferase K00640; Psort location: Cytoplasmic, score: 9.98.
     
 0.918
metA
Homoserine O-succinyltransferase; Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine; Belongs to the MetA family.
     
 0.915
pdxB-2
KEGG: cac:CAC0089 6.5e-73 serA; D-3-phosphoglycerate dehydrogenase K00058; Psort location: Cytoplasmic, score: 9.98; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
   
 
  0.787
EEP29462.1
KEGG: lac:LBA1841 2.4e-18 putative phosphoglycerate mutase K01834; Psort location: Cytoplasmic, score: 8.87.
    
  0.783
EEP29382.1
Transporter, dicarboxylate/amino acid:cation Na+/H+ symporter family protein; KEGG: lpp:lpp2199 2.4e-09 uracil phosphoribosyltransferase K03309; Psort location: CytoplasmicMembrane, score: 10.00; Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
  
    0.743
Your Current Organism:
Shuttleworthia satelles
NCBI taxonomy Id: 626523
Other names: S. satelles DSM 14600, Shuttleworthia satelles DSM 14600, Shuttleworthia satelles VPI D143K-13, Shuttleworthia satelles str. DSM 14600, Shuttleworthia satelles strain DSM 14600
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