STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EEP29395.1Putative A/G-specific adenine glycosylase; Adenine glycosylase active on G-A mispairs. (374 aa)    
Predicted Functional Partners:
xth
Exodeoxyribonuclease III; KEGG: lac:LBA0056 9.2e-90 exoA; exodeoxyribonuclease A K01142; Psort location: Cytoplasmic, score: 9.98.
    
 0.960
EEP29335.1
Hypothetical protein; KEGG: reh:H16_A2653 1.1e-09 G:T/U mismatch-specific DNA glycosylase K01249; Psort location: Cytoplasmic, score: 8.87.
    
 0.827
dnaN
DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]
    
 
 0.623
nth
Putative endonuclease III; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate.
 
 
0.615
msrB
methionine-R-sulfoxide reductase; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.
 
   
 0.602
polA
DNA-directed DNA polymerase; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
   
  
 0.602
EEP29396.1
Hypothetical protein; Psort location: Extracellular, score: 8.82.
       0.478
EEP28791.1
Hydrolase, NUDIX family; KEGG: fnu:FN1791 1.4e-40 mutator MutT protein K03574; Psort location: Cytoplasmic, score: 8.87.
 
 
 0.438
Your Current Organism:
Shuttleworthia satelles
NCBI taxonomy Id: 626523
Other names: S. satelles DSM 14600, Shuttleworthia satelles DSM 14600, Shuttleworthia satelles VPI D143K-13, Shuttleworthia satelles str. DSM 14600, Shuttleworthia satelles strain DSM 14600
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