STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EEP27362.1Vitamin B12 dependent methionine synthase, activation domain protein; KEGG: ctc:CTC01807 7.6e-31 putative 5-methyltetrahydrofolate--homocysteine methyltransferase K00548; Psort location: Cytoplasmic, score: 8.87. (224 aa)    
Predicted Functional Partners:
EEP27366.1
Homocysteine S-methyltransferase; KEGG: bcl:ABC1868 1.1e-56 5,10-methylenetetrahydrofolate reductase K00297; Psort location: Cytoplasmic, score: 8.87.
 
 
 0.995
EEP27364.1
KEGG: ctc:CTC01806 8.1e-185 5-methyltetrahydrofolate--homocysteine methyltransferase K00548; Psort location: Cytoplasmic, score: 8.87.
 
 
 0.991
nifJ
KEGG: ctc:CTC01741 0. pyruvate-flavodoxin oxidoreductase K03737.
    
 0.937
rnfB
Electron transport complex, RnfABCDGE type, B subunit; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane. Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfB subfamily.
 
  
 0.791
metG
methionine--tRNA ligase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation; Belongs to the class-I aminoacyl-tRNA synthetase family.
   
 
  0.790
fhs
KEGG: ban:BA2107 3.9e-194 fhs; formate--tetrahydrofolate ligase K01938; Psort location: Cytoplasmic, score: 8.87.
    
 0.750
metK
Methionine adenosyltransferase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
    
 0.749
EEP27365.1
Hypothetical protein; Psort location: Cytoplasmic, score: 8.87.
       0.737
glyA
Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
     
 0.736
EEP27363.1
Hypothetical protein.
       0.572
Your Current Organism:
Shuttleworthia satelles
NCBI taxonomy Id: 626523
Other names: S. satelles DSM 14600, Shuttleworthia satelles DSM 14600, Shuttleworthia satelles VPI D143K-13, Shuttleworthia satelles str. DSM 14600, Shuttleworthia satelles strain DSM 14600
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