STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EEP27532.1RelA/SpoT domain protein; KEGG: sph:MGAS10270_Spy0737 3.2e-48 GTP pyrophosphokinase K00951; Psort location: Cytoplasmic, score: 8.87. (224 aa)    
Predicted Functional Partners:
EEP29109.1
RelA/SpoT family protein; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.
     
 0.879
EEP27534.1
Histidine kinase A domain protein; KEGG: spi:MGAS10750_Spy0773 7.5e-72 sptS; two-component system histidine kinase; Psort location: CytoplasmicMembrane, score: 9.49.
 
     0.867
EEP27533.1
KEGG: rha:RHA1_ro05622 3.8e-36 response regulator (protein-glutamate methylesterase) K07669; Psort location: Cytoplasmic, score: 9.98.
  
  0.800
EEP29006.1
HD domain protein; KEGG: nph:NP3860A 4.4e-19 relA; probable GTP pyrophosphokinase K00951; Psort location: Cytoplasmic, score: 8.87.
     
 0.570
trmE
tRNA modification GTPase TrmE; Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
   
    0.558
gidA
tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA; NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34; Belongs to the MnmG family.
   
    0.543
EEP27680.1
ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein; KEGG: spj:MGAS2096_Spy0752 1.2e-57 sptS; two-component system histidine kinase; Psort location: CytoplasmicMembrane, score: 9.82.
 
     0.529
agcS-2
Amino acid carrier protein; KEGG: hpa:HPAG1_0925 1.1e-84 D-alanine glycine permease K01613; Psort location: CytoplasmicMembrane, score: 10.00.
       0.447
Your Current Organism:
Shuttleworthia satelles
NCBI taxonomy Id: 626523
Other names: S. satelles DSM 14600, Shuttleworthia satelles DSM 14600, Shuttleworthia satelles VPI D143K-13, Shuttleworthia satelles str. DSM 14600, Shuttleworthia satelles strain DSM 14600
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