STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ENO13204.1COG0266 Formamidopyrimidine-DNA glycosylase; Belongs to the FPG family. (266 aa)    
Predicted Functional Partners:
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
  
  
 0.960
ENO16171.1
COG0847 DNA polymerase III, epsilon subunit and related 3'-5' exonucleases.
  
 
 0.790
coaE
dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family.
  
  
 0.758
nth
Endonuclease III; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate.
   
  
 0.694
uvrC
Excinuclease ABC subunit C; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.
  
 
 0.681
ENO13205.1
COG0753 Catalase; Belongs to the catalase family.
       0.481
ENO13202.1
HAD superfamily hydrolase; COG0438 Glycosyltransferase.
 
     0.475
ENO13203.1
COG2120 Uncharacterized proteins, LmbE homologs.
       0.441
guaA
GMP synthase; Catalyzes the synthesis of GMP from XMP.
     
 0.431
ENO15303.1
16S rRNA m5C967 methyltransferase; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA.
  
    0.426
Your Current Organism:
Marinobacter nanhaiticus
NCBI taxonomy Id: 626887
Other names: M. nanhaiticus D15-8W, Marinobacter nanhaiticus D15-8W, Marinobacter sp. D15-8W
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.