node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ENO13323.1 | ENO15233.1 | J057_18045 | J057_07781 | Biotin biosynthesis protein BioH; COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily). | Acyltransferase; COG1020 Non-ribosomal peptide synthetase modules and related proteins. | 0.984 |
ENO13323.1 | ENO16383.1 | J057_18045 | J057_13551 | Biotin biosynthesis protein BioH; COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily). | 3-oxoacyl-ACP synthase; COG0304 3-oxoacyl-(acyl-carrier-protein) synthase; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family. | 0.534 |
ENO13323.1 | ENO16762.1 | J057_18045 | J057_03620 | Biotin biosynthesis protein BioH; COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily). | Amino acid adenylation domain-containing protein; COG1020 Non-ribosomal peptide synthetase modules and related proteins; overlaps another CDS with the same product name. | 0.996 |
ENO13323.1 | ENO16789.1 | J057_18045 | J057_03755 | Biotin biosynthesis protein BioH; COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily). | COG0304 3-oxoacyl-(acyl-carrier-protein) synthase; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family. | 0.534 |
ENO13323.1 | bioB | J057_18045 | J057_18035 | Biotin biosynthesis protein BioH; COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily). | Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. | 0.901 |
ENO13323.1 | bioC | J057_18045 | J057_18050 | Biotin biosynthesis protein BioH; COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily). | Hypothetical protein; Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl-L- methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway. | 0.972 |
ENO13323.1 | bioD | J057_18045 | J057_18055 | Biotin biosynthesis protein BioH; COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily). | Dethiobiotin synthetase; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring. | 0.907 |
ENO13323.1 | bioF | J057_18045 | J057_18040 | Biotin biosynthesis protein BioH; COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily). | 8-amino-7-oxononanoate synthase; Catalyzes the decarboxylative condensation of pimeloyl-[acyl- carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide. | 0.954 |
ENO13323.1 | fabF | J057_18045 | J057_19495 | Biotin biosynthesis protein BioH; COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily). | Beta-ketoacyl synthase; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. | 0.534 |
ENO13323.1 | metH | J057_18045 | J057_22360 | Biotin biosynthesis protein BioH; COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily). | B12-dependent methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.730 |
ENO15233.1 | ENO13323.1 | J057_07781 | J057_18045 | Acyltransferase; COG1020 Non-ribosomal peptide synthetase modules and related proteins. | Biotin biosynthesis protein BioH; COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily). | 0.984 |
ENO15233.1 | ENO16383.1 | J057_07781 | J057_13551 | Acyltransferase; COG1020 Non-ribosomal peptide synthetase modules and related proteins. | 3-oxoacyl-ACP synthase; COG0304 3-oxoacyl-(acyl-carrier-protein) synthase; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family. | 0.986 |
ENO15233.1 | ENO16762.1 | J057_07781 | J057_03620 | Acyltransferase; COG1020 Non-ribosomal peptide synthetase modules and related proteins. | Amino acid adenylation domain-containing protein; COG1020 Non-ribosomal peptide synthetase modules and related proteins; overlaps another CDS with the same product name. | 0.999 |
ENO15233.1 | ENO16789.1 | J057_07781 | J057_03755 | Acyltransferase; COG1020 Non-ribosomal peptide synthetase modules and related proteins. | COG0304 3-oxoacyl-(acyl-carrier-protein) synthase; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family. | 0.986 |
ENO15233.1 | bioC | J057_07781 | J057_18050 | Acyltransferase; COG1020 Non-ribosomal peptide synthetase modules and related proteins. | Hypothetical protein; Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl-L- methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway. | 0.759 |
ENO15233.1 | bioD | J057_07781 | J057_18055 | Acyltransferase; COG1020 Non-ribosomal peptide synthetase modules and related proteins. | Dethiobiotin synthetase; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring. | 0.491 |
ENO15233.1 | bioF | J057_07781 | J057_18040 | Acyltransferase; COG1020 Non-ribosomal peptide synthetase modules and related proteins. | 8-amino-7-oxononanoate synthase; Catalyzes the decarboxylative condensation of pimeloyl-[acyl- carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide. | 0.898 |
ENO15233.1 | fabF | J057_07781 | J057_19495 | Acyltransferase; COG1020 Non-ribosomal peptide synthetase modules and related proteins. | Beta-ketoacyl synthase; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. | 0.989 |
ENO15233.1 | metH | J057_07781 | J057_22360 | Acyltransferase; COG1020 Non-ribosomal peptide synthetase modules and related proteins. | B12-dependent methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.423 |
ENO16383.1 | ENO13323.1 | J057_13551 | J057_18045 | 3-oxoacyl-ACP synthase; COG0304 3-oxoacyl-(acyl-carrier-protein) synthase; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family. | Biotin biosynthesis protein BioH; COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily). | 0.534 |