STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KXK66943.1Hypothetical protein. (76 aa)    
Predicted Functional Partners:
dnaG
DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.
  
 
 0.721
KXK66676.1
Hypothetical protein; KEGG: hel:HELO_1001 0.0024 dnaA; chromosomal replication initiation protein K02313; Psort location: Cytoplasmic, score: 8.96.
  
 
 0.610
KXK66944.1
Putative holliday junction resolvase Hjc; Psort location: Cytoplasmic, score: 8.96.
       0.592
KXK65507.1
Hypothetical protein; Psort location: Cytoplasmic, score: 8.96.
  
 
 0.592
KXK66411.1
Toprim domain protein; Psort location: Cytoplasmic, score: 8.96.
  
 
 0.521
KXK66008.1
Hypothetical protein.
  
 
 0.521
KXK66009.1
Hypothetical protein.
  
 
 0.521
dnaA
Replication initiator protein DnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. Belongs to the DnaA family.
   
 
 0.492
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
  
  
 0.485
KXK64678.1
Hypothetical protein; Psort location: Cytoplasmic, score: 8.96.
   
 
 0.465
Your Current Organism:
Christensenella minuta
NCBI taxonomy Id: 626937
Other names: C. minuta, Catabacter sp. YIT 12065, Christensenella minuta Morotomi et al. 2012, DSM 22607, JCM 16072, YIT 12065
Server load: low (24%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.