STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KXK65796.1Putative methyltetrahydrofolate:corrinoid/iron-sulfur protein methyltransferase; KEGG: cce:Ccel_2473 5.7e-55 dihydropteroate synthase; K00548 5-methyltetrahydrofolate--homocysteine methyltransferase; Psort location: Cytoplasmic, score: 8.96. (264 aa)    
Predicted Functional Partners:
KXK65797.1
KEGG: ckr:CKR_1635 4.2e-130 bifunctional homocysteine S-methyltransferase/5,10-methylenetetrahydrofolate reductase protein; K00547 homocysteine S-methyltransferase; Psort location: Cytoplasmic, score: 9.97.
 
 0.999
KXK64243.1
Homocysteine S-methyltransferase; KEGG: dor:Desor_4523 6.3e-104 cobalamin-dependent methionine synthase I; K00548 5-methyltetrahydrofolate--homocysteine methyltransferase; Psort location: Cytoplasmic, score: 9.97.
 
 0.998
KXK64906.1
Putative dimethylamine corrinoid protein; KEGG: ssm:Spirs_2747 5.9e-60 methionine synthase; Psort location: Cytoplasmic, score: 9.97.
  
 0.982
fhs
Formate--tetrahydrofolate ligase; KEGG: scp:HMPREF0833_11151 2.9e-177 fhs2; formate-tetrahydrofolate ligase K01938; Psort location: Cytoplasmic, score: 8.96; Belongs to the formate--tetrahydrofolate ligase family.
    
 0.957
KXK64860.1
Adenosylhomocysteinase; KEGG: cth:Cthe_1200 8.5e-132 adenosylhomocysteinase K01251; Psort location: Cytoplasmic, score: 9.97.
    
 0.927
metK
Methionine adenosyltransferase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
    
 0.926
KXK64612.1
KEGG: cbt:CLH_0332 2.1e-160 O-acetylhomoserine aminocarboxypropyltransferase/cysteine synthase family protein; K01740 O-acetylhomoserine (thiol)-lyase; Psort location: Cytoplasmic, score: 9.97.
  
 
 0.922
KXK64290.1
O-acetylhomoserine aminocarboxypropyltransferase/cysteine synthase; KEGG: cls:CXIVA_13540 5.2e-180 ET17; O-acetylhomoserine sulfhydrylase; K01740 O-acetylhomoserine (thiol)-lyase; Psort location: Cytoplasmic, score: 9.97.
  
 
 0.922
thyX
Thymidylate synthase, flavin-dependent; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant.
 
  
 0.919
glyA
Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
     
 0.919
Your Current Organism:
Christensenella minuta
NCBI taxonomy Id: 626937
Other names: C. minuta, Catabacter sp. YIT 12065, Christensenella minuta Morotomi et al. 2012, DSM 22607, JCM 16072, YIT 12065
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