node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CoaBC | metK | HMPREF3293_02213 | HMPREF3293_01818 | Phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | Methionine adenosyltransferase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. | 0.805 |
KXK64243.1 | KXK64860.1 | HMPREF3293_02887 | HMPREF3293_02105 | Homocysteine S-methyltransferase; KEGG: dor:Desor_4523 6.3e-104 cobalamin-dependent methionine synthase I; K00548 5-methyltetrahydrofolate--homocysteine methyltransferase; Psort location: Cytoplasmic, score: 9.97. | Adenosylhomocysteinase; KEGG: cth:Cthe_1200 8.5e-132 adenosylhomocysteinase K01251; Psort location: Cytoplasmic, score: 9.97. | 0.922 |
KXK64243.1 | KXK65796.1 | HMPREF3293_02887 | HMPREF3293_01289 | Homocysteine S-methyltransferase; KEGG: dor:Desor_4523 6.3e-104 cobalamin-dependent methionine synthase I; K00548 5-methyltetrahydrofolate--homocysteine methyltransferase; Psort location: Cytoplasmic, score: 9.97. | Putative methyltetrahydrofolate:corrinoid/iron-sulfur protein methyltransferase; KEGG: cce:Ccel_2473 5.7e-55 dihydropteroate synthase; K00548 5-methyltetrahydrofolate--homocysteine methyltransferase; Psort location: Cytoplasmic, score: 8.96. | 0.998 |
KXK64243.1 | KXK65797.1 | HMPREF3293_02887 | HMPREF3293_01290 | Homocysteine S-methyltransferase; KEGG: dor:Desor_4523 6.3e-104 cobalamin-dependent methionine synthase I; K00548 5-methyltetrahydrofolate--homocysteine methyltransferase; Psort location: Cytoplasmic, score: 9.97. | KEGG: ckr:CKR_1635 4.2e-130 bifunctional homocysteine S-methyltransferase/5,10-methylenetetrahydrofolate reductase protein; K00547 homocysteine S-methyltransferase; Psort location: Cytoplasmic, score: 9.97. | 0.970 |
KXK64243.1 | metK | HMPREF3293_02887 | HMPREF3293_01818 | Homocysteine S-methyltransferase; KEGG: dor:Desor_4523 6.3e-104 cobalamin-dependent methionine synthase I; K00548 5-methyltetrahydrofolate--homocysteine methyltransferase; Psort location: Cytoplasmic, score: 9.97. | Methionine adenosyltransferase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. | 0.921 |
KXK64860.1 | KXK64243.1 | HMPREF3293_02105 | HMPREF3293_02887 | Adenosylhomocysteinase; KEGG: cth:Cthe_1200 8.5e-132 adenosylhomocysteinase K01251; Psort location: Cytoplasmic, score: 9.97. | Homocysteine S-methyltransferase; KEGG: dor:Desor_4523 6.3e-104 cobalamin-dependent methionine synthase I; K00548 5-methyltetrahydrofolate--homocysteine methyltransferase; Psort location: Cytoplasmic, score: 9.97. | 0.922 |
KXK64860.1 | KXK65764.1 | HMPREF3293_02105 | HMPREF3293_01367 | Adenosylhomocysteinase; KEGG: cth:Cthe_1200 8.5e-132 adenosylhomocysteinase K01251; Psort location: Cytoplasmic, score: 9.97. | KEGG: gsk:KN400_0411 1.1e-124 DNA cytosine methyltransferase; K00558 DNA (cytosine-5-)-methyltransferase; Psort location: Cytoplasmic, score: 8.96; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. | 0.908 |
KXK64860.1 | KXK65796.1 | HMPREF3293_02105 | HMPREF3293_01289 | Adenosylhomocysteinase; KEGG: cth:Cthe_1200 8.5e-132 adenosylhomocysteinase K01251; Psort location: Cytoplasmic, score: 9.97. | Putative methyltetrahydrofolate:corrinoid/iron-sulfur protein methyltransferase; KEGG: cce:Ccel_2473 5.7e-55 dihydropteroate synthase; K00548 5-methyltetrahydrofolate--homocysteine methyltransferase; Psort location: Cytoplasmic, score: 8.96. | 0.927 |
KXK64860.1 | KXK65797.1 | HMPREF3293_02105 | HMPREF3293_01290 | Adenosylhomocysteinase; KEGG: cth:Cthe_1200 8.5e-132 adenosylhomocysteinase K01251; Psort location: Cytoplasmic, score: 9.97. | KEGG: ckr:CKR_1635 4.2e-130 bifunctional homocysteine S-methyltransferase/5,10-methylenetetrahydrofolate reductase protein; K00547 homocysteine S-methyltransferase; Psort location: Cytoplasmic, score: 9.97. | 0.970 |
KXK64860.1 | guaA | HMPREF3293_02105 | HMPREF3293_02115 | Adenosylhomocysteinase; KEGG: cth:Cthe_1200 8.5e-132 adenosylhomocysteinase K01251; Psort location: Cytoplasmic, score: 9.97. | GMP synthase domain protein; Catalyzes the synthesis of GMP from XMP. | 0.526 |
KXK64860.1 | metK | HMPREF3293_02105 | HMPREF3293_01818 | Adenosylhomocysteinase; KEGG: cth:Cthe_1200 8.5e-132 adenosylhomocysteinase K01251; Psort location: Cytoplasmic, score: 9.97. | Methionine adenosyltransferase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. | 0.758 |
KXK65227.1 | metK | HMPREF3293_01816 | HMPREF3293_01818 | comF family protein; KEGG: nde:NIDE1089 1.4e-17 putative phosphoribosyltransferase; Psort location: Cytoplasmic, score: 9.97. | Methionine adenosyltransferase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. | 0.812 |
KXK65227.1 | recD2 | HMPREF3293_01816 | HMPREF3293_01817 | comF family protein; KEGG: nde:NIDE1089 1.4e-17 putative phosphoribosyltransferase; Psort location: Cytoplasmic, score: 9.97. | Helicase, RecD/TraA family; DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity; Belongs to the RecD family. RecD-like subfamily. | 0.812 |
KXK65764.1 | KXK64860.1 | HMPREF3293_01367 | HMPREF3293_02105 | KEGG: gsk:KN400_0411 1.1e-124 DNA cytosine methyltransferase; K00558 DNA (cytosine-5-)-methyltransferase; Psort location: Cytoplasmic, score: 8.96; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. | Adenosylhomocysteinase; KEGG: cth:Cthe_1200 8.5e-132 adenosylhomocysteinase K01251; Psort location: Cytoplasmic, score: 9.97. | 0.908 |
KXK65764.1 | metK | HMPREF3293_01367 | HMPREF3293_01818 | KEGG: gsk:KN400_0411 1.1e-124 DNA cytosine methyltransferase; K00558 DNA (cytosine-5-)-methyltransferase; Psort location: Cytoplasmic, score: 8.96; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. | Methionine adenosyltransferase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. | 0.917 |
KXK65764.1 | speD | HMPREF3293_01367 | HMPREF3293_00353 | KEGG: gsk:KN400_0411 1.1e-124 DNA cytosine methyltransferase; K00558 DNA (cytosine-5-)-methyltransferase; Psort location: Cytoplasmic, score: 8.96; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. | S-adenosylmethionine decarboxylase proenzyme; Catalyzes the decarboxylation of S-adenosylmethionine to S- adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine; Belongs to the prokaryotic AdoMetDC family. Type 2 subfamily. | 0.900 |
KXK65796.1 | KXK64243.1 | HMPREF3293_01289 | HMPREF3293_02887 | Putative methyltetrahydrofolate:corrinoid/iron-sulfur protein methyltransferase; KEGG: cce:Ccel_2473 5.7e-55 dihydropteroate synthase; K00548 5-methyltetrahydrofolate--homocysteine methyltransferase; Psort location: Cytoplasmic, score: 8.96. | Homocysteine S-methyltransferase; KEGG: dor:Desor_4523 6.3e-104 cobalamin-dependent methionine synthase I; K00548 5-methyltetrahydrofolate--homocysteine methyltransferase; Psort location: Cytoplasmic, score: 9.97. | 0.998 |
KXK65796.1 | KXK64860.1 | HMPREF3293_01289 | HMPREF3293_02105 | Putative methyltetrahydrofolate:corrinoid/iron-sulfur protein methyltransferase; KEGG: cce:Ccel_2473 5.7e-55 dihydropteroate synthase; K00548 5-methyltetrahydrofolate--homocysteine methyltransferase; Psort location: Cytoplasmic, score: 8.96. | Adenosylhomocysteinase; KEGG: cth:Cthe_1200 8.5e-132 adenosylhomocysteinase K01251; Psort location: Cytoplasmic, score: 9.97. | 0.927 |
KXK65796.1 | KXK65797.1 | HMPREF3293_01289 | HMPREF3293_01290 | Putative methyltetrahydrofolate:corrinoid/iron-sulfur protein methyltransferase; KEGG: cce:Ccel_2473 5.7e-55 dihydropteroate synthase; K00548 5-methyltetrahydrofolate--homocysteine methyltransferase; Psort location: Cytoplasmic, score: 8.96. | KEGG: ckr:CKR_1635 4.2e-130 bifunctional homocysteine S-methyltransferase/5,10-methylenetetrahydrofolate reductase protein; K00547 homocysteine S-methyltransferase; Psort location: Cytoplasmic, score: 9.97. | 0.999 |
KXK65796.1 | metK | HMPREF3293_01289 | HMPREF3293_01818 | Putative methyltetrahydrofolate:corrinoid/iron-sulfur protein methyltransferase; KEGG: cce:Ccel_2473 5.7e-55 dihydropteroate synthase; K00548 5-methyltetrahydrofolate--homocysteine methyltransferase; Psort location: Cytoplasmic, score: 8.96. | Methionine adenosyltransferase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. | 0.926 |