node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
KXK64777.1 | KXK64779.1 | HMPREF3293_02016 | HMPREF3293_02018 | Hypothetical protein; Psort location: CytoplasmicMembrane, score: 9.86. | Protein FolC; KEGG: cth:Cthe_1384 1.6e-50 FolC bifunctional protein; K11754 dihydrofolate synthase / folylpolyglutamate synthase; Psort location: Cytoplasmic, score: 9.97. | 0.727 |
KXK64777.1 | ppk | HMPREF3293_02016 | HMPREF3293_02015 | Hypothetical protein; Psort location: CytoplasmicMembrane, score: 9.86. | Polyphosphate kinase 1; Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP). Belongs to the polyphosphate kinase 1 (PPK1) family. | 0.531 |
KXK64777.1 | valS | HMPREF3293_02016 | HMPREF3293_02017 | Hypothetical protein; Psort location: CytoplasmicMembrane, score: 9.86. | valine--tRNA ligase; Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA- dependent manner; Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily. | 0.727 |
KXK64779.1 | KXK64777.1 | HMPREF3293_02018 | HMPREF3293_02016 | Protein FolC; KEGG: cth:Cthe_1384 1.6e-50 FolC bifunctional protein; K11754 dihydrofolate synthase / folylpolyglutamate synthase; Psort location: Cytoplasmic, score: 9.97. | Hypothetical protein; Psort location: CytoplasmicMembrane, score: 9.86. | 0.727 |
KXK64779.1 | KXK65123.1 | HMPREF3293_02018 | HMPREF3293_02381 | Protein FolC; KEGG: cth:Cthe_1384 1.6e-50 FolC bifunctional protein; K11754 dihydrofolate synthase / folylpolyglutamate synthase; Psort location: Cytoplasmic, score: 9.97. | Riboflavin biosynthesis protein RibF; KEGG: ccl:Clocl_2449 1.6e-52 riboflavin kinase/FMN adenylyltransferase; K11753 riboflavin kinase / FMN adenylyltransferase; Psort location: Cytoplasmic, score: 9.97; Belongs to the ribF family. | 0.486 |
KXK64779.1 | KXK65147.1 | HMPREF3293_02018 | HMPREF3293_02405 | Protein FolC; KEGG: cth:Cthe_1384 1.6e-50 FolC bifunctional protein; K11754 dihydrofolate synthase / folylpolyglutamate synthase; Psort location: Cytoplasmic, score: 9.97. | KEGG: toc:Toce_0352 5.0e-31 5-formyltetrahydrofolate cyclo-ligase; K01934 5-formyltetrahydrofolate cyclo-ligase; Psort location: Cytoplasmic, score: 8.96. | 0.683 |
KXK64779.1 | KXK66077.1 | HMPREF3293_02018 | HMPREF3293_00812 | Protein FolC; KEGG: cth:Cthe_1384 1.6e-50 FolC bifunctional protein; K11754 dihydrofolate synthase / folylpolyglutamate synthase; Psort location: Cytoplasmic, score: 9.97. | N-acetylmuramoyl-L-alanine amidase; KEGG: cbe:Cbei_4698 2.6e-07 cell wall hydrolase/autolysin; K01448 N-acetylmuramoyl-L-alanine amidase. | 0.507 |
KXK64779.1 | guaA | HMPREF3293_02018 | HMPREF3293_02115 | Protein FolC; KEGG: cth:Cthe_1384 1.6e-50 FolC bifunctional protein; K11754 dihydrofolate synthase / folylpolyglutamate synthase; Psort location: Cytoplasmic, score: 9.97. | GMP synthase domain protein; Catalyzes the synthesis of GMP from XMP. | 0.749 |
KXK64779.1 | ispH | HMPREF3293_02018 | HMPREF3293_02300 | Protein FolC; KEGG: cth:Cthe_1384 1.6e-50 FolC bifunctional protein; K11754 dihydrofolate synthase / folylpolyglutamate synthase; Psort location: Cytoplasmic, score: 9.97. | 4-hydroxy-3-methylbut-2-enyl diphosphate reductase; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. Belongs to the IspH family. | 0.495 |
KXK64779.1 | ppk | HMPREF3293_02018 | HMPREF3293_02015 | Protein FolC; KEGG: cth:Cthe_1384 1.6e-50 FolC bifunctional protein; K11754 dihydrofolate synthase / folylpolyglutamate synthase; Psort location: Cytoplasmic, score: 9.97. | Polyphosphate kinase 1; Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP). Belongs to the polyphosphate kinase 1 (PPK1) family. | 0.547 |
KXK64779.1 | purA | HMPREF3293_02018 | HMPREF3293_02652 | Protein FolC; KEGG: cth:Cthe_1384 1.6e-50 FolC bifunctional protein; K11754 dihydrofolate synthase / folylpolyglutamate synthase; Psort location: Cytoplasmic, score: 9.97. | Adenylosuccinate synthase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. | 0.519 |
KXK64779.1 | trpD | HMPREF3293_02018 | HMPREF3293_00997 | Protein FolC; KEGG: cth:Cthe_1384 1.6e-50 FolC bifunctional protein; K11754 dihydrofolate synthase / folylpolyglutamate synthase; Psort location: Cytoplasmic, score: 9.97. | Anthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). | 0.681 |
KXK64779.1 | valS | HMPREF3293_02018 | HMPREF3293_02017 | Protein FolC; KEGG: cth:Cthe_1384 1.6e-50 FolC bifunctional protein; K11754 dihydrofolate synthase / folylpolyglutamate synthase; Psort location: Cytoplasmic, score: 9.97. | valine--tRNA ligase; Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA- dependent manner; Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily. | 0.879 |
KXK65123.1 | KXK64779.1 | HMPREF3293_02381 | HMPREF3293_02018 | Riboflavin biosynthesis protein RibF; KEGG: ccl:Clocl_2449 1.6e-52 riboflavin kinase/FMN adenylyltransferase; K11753 riboflavin kinase / FMN adenylyltransferase; Psort location: Cytoplasmic, score: 9.97; Belongs to the ribF family. | Protein FolC; KEGG: cth:Cthe_1384 1.6e-50 FolC bifunctional protein; K11754 dihydrofolate synthase / folylpolyglutamate synthase; Psort location: Cytoplasmic, score: 9.97. | 0.486 |
KXK65123.1 | guaA | HMPREF3293_02381 | HMPREF3293_02115 | Riboflavin biosynthesis protein RibF; KEGG: ccl:Clocl_2449 1.6e-52 riboflavin kinase/FMN adenylyltransferase; K11753 riboflavin kinase / FMN adenylyltransferase; Psort location: Cytoplasmic, score: 9.97; Belongs to the ribF family. | GMP synthase domain protein; Catalyzes the synthesis of GMP from XMP. | 0.517 |
KXK65123.1 | ispH | HMPREF3293_02381 | HMPREF3293_02300 | Riboflavin biosynthesis protein RibF; KEGG: ccl:Clocl_2449 1.6e-52 riboflavin kinase/FMN adenylyltransferase; K11753 riboflavin kinase / FMN adenylyltransferase; Psort location: Cytoplasmic, score: 9.97; Belongs to the ribF family. | 4-hydroxy-3-methylbut-2-enyl diphosphate reductase; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. Belongs to the IspH family. | 0.529 |
KXK65147.1 | KXK64779.1 | HMPREF3293_02405 | HMPREF3293_02018 | KEGG: toc:Toce_0352 5.0e-31 5-formyltetrahydrofolate cyclo-ligase; K01934 5-formyltetrahydrofolate cyclo-ligase; Psort location: Cytoplasmic, score: 8.96. | Protein FolC; KEGG: cth:Cthe_1384 1.6e-50 FolC bifunctional protein; K11754 dihydrofolate synthase / folylpolyglutamate synthase; Psort location: Cytoplasmic, score: 9.97. | 0.683 |
KXK66077.1 | KXK64779.1 | HMPREF3293_00812 | HMPREF3293_02018 | N-acetylmuramoyl-L-alanine amidase; KEGG: cbe:Cbei_4698 2.6e-07 cell wall hydrolase/autolysin; K01448 N-acetylmuramoyl-L-alanine amidase. | Protein FolC; KEGG: cth:Cthe_1384 1.6e-50 FolC bifunctional protein; K11754 dihydrofolate synthase / folylpolyglutamate synthase; Psort location: Cytoplasmic, score: 9.97. | 0.507 |
guaA | KXK64779.1 | HMPREF3293_02115 | HMPREF3293_02018 | GMP synthase domain protein; Catalyzes the synthesis of GMP from XMP. | Protein FolC; KEGG: cth:Cthe_1384 1.6e-50 FolC bifunctional protein; K11754 dihydrofolate synthase / folylpolyglutamate synthase; Psort location: Cytoplasmic, score: 9.97. | 0.749 |
guaA | KXK65123.1 | HMPREF3293_02115 | HMPREF3293_02381 | GMP synthase domain protein; Catalyzes the synthesis of GMP from XMP. | Riboflavin biosynthesis protein RibF; KEGG: ccl:Clocl_2449 1.6e-52 riboflavin kinase/FMN adenylyltransferase; K11753 riboflavin kinase / FMN adenylyltransferase; Psort location: Cytoplasmic, score: 9.97; Belongs to the ribF family. | 0.517 |