node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
KXK64449.1 | KXK64639.1 | HMPREF3293_02528 | HMPREF3293_02719 | HD domain protein; KEGG: gpb:HDN1F_31970 2.0e-50 hydrolase of HD superfamily; K08722 5'-nucleotidase; Psort location: Cytoplasmic, score: 8.96. | 5'-nucleotidase protein; KEGG: sbu:SpiBuddy_1928 6.3e-60 5'-nucleotidase; Psort location: Periplasmic, score: 9.76; Belongs to the 5'-nucleotidase family. | 0.910 |
KXK64449.1 | KXK64927.1 | HMPREF3293_02528 | HMPREF3293_02175 | HD domain protein; KEGG: gpb:HDN1F_31970 2.0e-50 hydrolase of HD superfamily; K08722 5'-nucleotidase; Psort location: Cytoplasmic, score: 8.96. | ComE operon protein 2 family protein; KEGG: clc:Calla_1764 1.9e-40 zinc-binding CMP/dCMP deaminase; K01493 dCMP deaminase; Psort location: Cytoplasmic, score: 8.96. | 0.900 |
KXK64449.1 | KXK65109.1 | HMPREF3293_02528 | HMPREF3293_02367 | HD domain protein; KEGG: gpb:HDN1F_31970 2.0e-50 hydrolase of HD superfamily; K08722 5'-nucleotidase; Psort location: Cytoplasmic, score: 8.96. | Putative purine nucleoside phosphorylase I, inosine and guanosine-specific; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. | 0.910 |
KXK64449.1 | KXK66386.1 | HMPREF3293_02528 | HMPREF3293_00792 | HD domain protein; KEGG: gpb:HDN1F_31970 2.0e-50 hydrolase of HD superfamily; K08722 5'-nucleotidase; Psort location: Cytoplasmic, score: 8.96. | KEGG: sgo:SGO_1247 3.1e-63 5'-nucleotidase K01081; Belongs to the 5'-nucleotidase family. | 0.910 |
KXK64449.1 | ThiT | HMPREF3293_02528 | HMPREF3293_02529 | HD domain protein; KEGG: gpb:HDN1F_31970 2.0e-50 hydrolase of HD superfamily; K08722 5'-nucleotidase; Psort location: Cytoplasmic, score: 8.96. | Putative proton-coupled thiamine transporter YuaJ; Psort location: CytoplasmicMembrane, score: 10.00. | 0.572 |
KXK64449.1 | cmk | HMPREF3293_02528 | HMPREF3293_02298 | HD domain protein; KEGG: gpb:HDN1F_31970 2.0e-50 hydrolase of HD superfamily; K08722 5'-nucleotidase; Psort location: Cytoplasmic, score: 8.96. | Cytidylate kinase; KEGG: mas:Mahau_1600 4.3e-57 cytidylate kinase K00945; Psort location: Cytoplasmic, score: 9.97. | 0.903 |
KXK64449.1 | dut | HMPREF3293_02528 | HMPREF3293_01543 | HD domain protein; KEGG: gpb:HDN1F_31970 2.0e-50 hydrolase of HD superfamily; K08722 5'-nucleotidase; Psort location: Cytoplasmic, score: 8.96. | Putative dUTP diphosphatase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family. | 0.903 |
KXK64449.1 | surE | HMPREF3293_02528 | HMPREF3293_02357 | HD domain protein; KEGG: gpb:HDN1F_31970 2.0e-50 hydrolase of HD superfamily; K08722 5'-nucleotidase; Psort location: Cytoplasmic, score: 8.96. | 5'/3'-nucleotidase SurE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. | 0.915 |
KXK64449.1 | thyX | HMPREF3293_02528 | HMPREF3293_01168 | HD domain protein; KEGG: gpb:HDN1F_31970 2.0e-50 hydrolase of HD superfamily; K08722 5'-nucleotidase; Psort location: Cytoplasmic, score: 8.96. | Thymidylate synthase, flavin-dependent; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant. | 0.904 |
KXK64449.1 | tmk | HMPREF3293_02528 | HMPREF3293_01910 | HD domain protein; KEGG: gpb:HDN1F_31970 2.0e-50 hydrolase of HD superfamily; K08722 5'-nucleotidase; Psort location: Cytoplasmic, score: 8.96. | dTMP kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family. | 0.909 |
KXK64639.1 | KXK64449.1 | HMPREF3293_02719 | HMPREF3293_02528 | 5'-nucleotidase protein; KEGG: sbu:SpiBuddy_1928 6.3e-60 5'-nucleotidase; Psort location: Periplasmic, score: 9.76; Belongs to the 5'-nucleotidase family. | HD domain protein; KEGG: gpb:HDN1F_31970 2.0e-50 hydrolase of HD superfamily; K08722 5'-nucleotidase; Psort location: Cytoplasmic, score: 8.96. | 0.910 |
KXK64639.1 | KXK64927.1 | HMPREF3293_02719 | HMPREF3293_02175 | 5'-nucleotidase protein; KEGG: sbu:SpiBuddy_1928 6.3e-60 5'-nucleotidase; Psort location: Periplasmic, score: 9.76; Belongs to the 5'-nucleotidase family. | ComE operon protein 2 family protein; KEGG: clc:Calla_1764 1.9e-40 zinc-binding CMP/dCMP deaminase; K01493 dCMP deaminase; Psort location: Cytoplasmic, score: 8.96. | 0.907 |
KXK64639.1 | KXK65109.1 | HMPREF3293_02719 | HMPREF3293_02367 | 5'-nucleotidase protein; KEGG: sbu:SpiBuddy_1928 6.3e-60 5'-nucleotidase; Psort location: Periplasmic, score: 9.76; Belongs to the 5'-nucleotidase family. | Putative purine nucleoside phosphorylase I, inosine and guanosine-specific; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. | 0.919 |
KXK64639.1 | KXK66386.1 | HMPREF3293_02719 | HMPREF3293_00792 | 5'-nucleotidase protein; KEGG: sbu:SpiBuddy_1928 6.3e-60 5'-nucleotidase; Psort location: Periplasmic, score: 9.76; Belongs to the 5'-nucleotidase family. | KEGG: sgo:SGO_1247 3.1e-63 5'-nucleotidase K01081; Belongs to the 5'-nucleotidase family. | 0.929 |
KXK64639.1 | cmk | HMPREF3293_02719 | HMPREF3293_02298 | 5'-nucleotidase protein; KEGG: sbu:SpiBuddy_1928 6.3e-60 5'-nucleotidase; Psort location: Periplasmic, score: 9.76; Belongs to the 5'-nucleotidase family. | Cytidylate kinase; KEGG: mas:Mahau_1600 4.3e-57 cytidylate kinase K00945; Psort location: Cytoplasmic, score: 9.97. | 0.900 |
KXK64639.1 | dut | HMPREF3293_02719 | HMPREF3293_01543 | 5'-nucleotidase protein; KEGG: sbu:SpiBuddy_1928 6.3e-60 5'-nucleotidase; Psort location: Periplasmic, score: 9.76; Belongs to the 5'-nucleotidase family. | Putative dUTP diphosphatase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family. | 0.901 |
KXK64639.1 | surE | HMPREF3293_02719 | HMPREF3293_02357 | 5'-nucleotidase protein; KEGG: sbu:SpiBuddy_1928 6.3e-60 5'-nucleotidase; Psort location: Periplasmic, score: 9.76; Belongs to the 5'-nucleotidase family. | 5'/3'-nucleotidase SurE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. | 0.912 |
KXK64639.1 | thyX | HMPREF3293_02719 | HMPREF3293_01168 | 5'-nucleotidase protein; KEGG: sbu:SpiBuddy_1928 6.3e-60 5'-nucleotidase; Psort location: Periplasmic, score: 9.76; Belongs to the 5'-nucleotidase family. | Thymidylate synthase, flavin-dependent; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant. | 0.900 |
KXK64639.1 | tmk | HMPREF3293_02719 | HMPREF3293_01910 | 5'-nucleotidase protein; KEGG: sbu:SpiBuddy_1928 6.3e-60 5'-nucleotidase; Psort location: Periplasmic, score: 9.76; Belongs to the 5'-nucleotidase family. | dTMP kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family. | 0.915 |
KXK64927.1 | KXK64449.1 | HMPREF3293_02175 | HMPREF3293_02528 | ComE operon protein 2 family protein; KEGG: clc:Calla_1764 1.9e-40 zinc-binding CMP/dCMP deaminase; K01493 dCMP deaminase; Psort location: Cytoplasmic, score: 8.96. | HD domain protein; KEGG: gpb:HDN1F_31970 2.0e-50 hydrolase of HD superfamily; K08722 5'-nucleotidase; Psort location: Cytoplasmic, score: 8.96. | 0.900 |