Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
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Score
SLG_00860Hypothetical protein. (133 aa)    
Predicted Functional Partners:
folK
2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase; Protein synonym:6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase; protein synonym:7, 8-dihydro-6-hydroxymethylpterin-pyrophosphokinase.
  
 
 0.972
folP
Dihydropteroate synthase; Protein synonym:DHPS; protein synonym:dihydropteroate pyrophosphorylase.
  
  
 0.947
folE
GTP cyclohydrolase I.
  
  
 0.947
folC
Protein synonym:folylpoly-gamma-glutamate synthetase; protein synonym:tetrahydrofolate synthase; protein synonym:tetrahydrofolylpolyglutamate synthase.
  
  
 0.675
ribD
Diaminohydroxyphosphoribosylaminopyrimidine deaminase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family.
  
  
 0.654
ispD/ispF
2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase; Bifunctional enzyme that catalyzes the formation of 4- diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D- erythritol 4-phosphate (MEP) (IspD), and catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C- methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (IspF).
  
  
 0.640
SLG_00870
Putative acetyltransferase.
       0.628
SLG_37010
Para-aminobenzoate synthetase component I.
  
  
 0.617
SLG_00880
Hypothetical protein.
       0.579
SLG_05030
Nucleoside-triphosphatase; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family.
  
  
 0.552
Your Current Organism:
Sphingobium sp. SYK6
NCBI taxonomy Id: 627192
Other names: S. sp. SYK-6, Sphingobium sp. SYK-6
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