Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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gene co-occurrence
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[Homology]
Score
hemBDelta-aminolevulinic acid dehydratase; Protein synonym:porphobilinogen synthase; Belongs to the ALAD family. (334 aa)    
Predicted Functional Partners:
hemC
Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family.
 
 0.996
cobA
uroporphyrinogen-III C-methyltransferase; Protein synonym:SUMT.
 
  
 0.935
SLG_20350
5-aminolevulinate synthase.
    
 0.916
cobA-2
uroporphyrinogen-III C-methyltransferase; Protein synonym:SUMT.
 
  
 0.870
SLG_00510
uroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III.
  
 
 0.867
SLG_00940
Putative acetyltransferase.
       0.853
SLG_00950
Conserved hypothetical protein.
       0.853
hemE
Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
 
 
 0.831
hemF
Coproporphyrinogen III oxidase.
 
 
 0.658
hemH
Ferrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family.
 
  
 0.629
Your Current Organism:
Sphingobium sp. SYK6
NCBI taxonomy Id: 627192
Other names: S. sp. SYK-6, Sphingobium sp. SYK-6
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