| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| SLG_22820 | SLG_26810 | SLG_22820 | SLG_26810 | Small heat shock protein; Belongs to the small heat shock protein (HSP20) family. | Hypothetical protein. | 0.491 |
| SLG_22820 | SLG_37150 | SLG_22820 | SLG_37150 | Small heat shock protein; Belongs to the small heat shock protein (HSP20) family. | Hsp70 family protein. | 0.410 |
| SLG_22820 | clpB | SLG_22820 | SLG_02410 | Small heat shock protein; Belongs to the small heat shock protein (HSP20) family. | Chaperone protein ClpB; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family. | 0.627 |
| SLG_22820 | dnaJ | SLG_22820 | SLG_16090 | Small heat shock protein; Belongs to the small heat shock protein (HSP20) family. | Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...] | 0.404 |
| SLG_22820 | dnaK | SLG_22820 | SLG_16080 | Small heat shock protein; Belongs to the small heat shock protein (HSP20) family. | Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.458 |
| SLG_22820 | grpE | SLG_22820 | SLG_05060 | Small heat shock protein; Belongs to the small heat shock protein (HSP20) family. | Protein GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent i [...] | 0.420 |
| SLG_26780 | SLG_26810 | SLG_26780 | SLG_26810 | Small heat shock protein; Belongs to the small heat shock protein (HSP20) family. | Hypothetical protein. | 0.491 |
| SLG_26780 | SLG_37150 | SLG_26780 | SLG_37150 | Small heat shock protein; Belongs to the small heat shock protein (HSP20) family. | Hsp70 family protein. | 0.410 |
| SLG_26780 | clpB | SLG_26780 | SLG_02410 | Small heat shock protein; Belongs to the small heat shock protein (HSP20) family. | Chaperone protein ClpB; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family. | 0.627 |
| SLG_26780 | dnaJ | SLG_26780 | SLG_16090 | Small heat shock protein; Belongs to the small heat shock protein (HSP20) family. | Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...] | 0.404 |
| SLG_26780 | dnaK | SLG_26780 | SLG_16080 | Small heat shock protein; Belongs to the small heat shock protein (HSP20) family. | Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.458 |
| SLG_26780 | grpE | SLG_26780 | SLG_05060 | Small heat shock protein; Belongs to the small heat shock protein (HSP20) family. | Protein GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent i [...] | 0.420 |
| SLG_26810 | SLG_22820 | SLG_26810 | SLG_22820 | Hypothetical protein. | Small heat shock protein; Belongs to the small heat shock protein (HSP20) family. | 0.491 |
| SLG_26810 | SLG_26780 | SLG_26810 | SLG_26780 | Hypothetical protein. | Small heat shock protein; Belongs to the small heat shock protein (HSP20) family. | 0.491 |
| SLG_26810 | SLG_37150 | SLG_26810 | SLG_37150 | Hypothetical protein. | Hsp70 family protein. | 0.971 |
| SLG_26810 | clpB | SLG_26810 | SLG_02410 | Hypothetical protein. | Chaperone protein ClpB; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family. | 0.686 |
| SLG_26810 | clpP | SLG_26810 | SLG_20500 | Hypothetical protein. | ATP-dependent Clp protease proteolytic subunit; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | 0.529 |
| SLG_26810 | dnaJ | SLG_26810 | SLG_16090 | Hypothetical protein. | Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...] | 0.721 |
| SLG_26810 | dnaK | SLG_26810 | SLG_16080 | Hypothetical protein. | Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.971 |
| SLG_26810 | groEL | SLG_26810 | SLG_00820 | Hypothetical protein. | 60 kDa chaperonin; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. | 0.793 |
STRING v12.5 is now available!
