Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
SLG_08490DNA-3-methyladenine glycosylase II. (204 aa)    
Predicted Functional Partners:
ogt
methylated-DNA--protein-cysteine methyltransferase; Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
 
  
 0.778
ada
Protein synonym:regulatory protein of adaptative response.
 
  
 0.746
ligXc
Ferredoxin; Involved in the catabolism of 5,5'-dehydrodivanillate (DDVA), an intermediate in the biodegradation of lignin. Part of a three- component monooxygenase that catalyzes the O-demethylation of DDVA, leading to the formation of 2,2',3-trihydroxy-3'-methoxy-5,5'- dicarboxybiphenyl (OH-DDVA). LigXc probably functions as an intermediate electron transfer protein between LigXd and LigXa. Belongs to the adrenodoxin/putidaredoxin family.
       0.611
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
   
 
 0.603
xthA
Exodeoxyribonuclease III; Protein synonym:AP endonuclease VI.
   
 0.493
xthA-2
Exodeoxyribonuclease III; Protein synonym:AP endonuclease VI.
   
 0.493
xthA-3
Exodeoxyribonuclease III; Protein synonym:AP endonuclease VI.
   
 0.493
nth
Putative endonuclease III; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate.
 
 
 
 0.445
recO
DNA repair protein RecO; Involved in DNA repair and RecF pathway recombination.
     
 0.418
mutY
Putative A/G-specific adenine glycosylase; Adenine glycosylase active on G-A mispairs.
   
  
 0.415
Your Current Organism:
Sphingobium sp. SYK6
NCBI taxonomy Id: 627192
Other names: S. sp. SYK-6, Sphingobium sp. SYK-6
Server load: medium (54%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.