node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
NAV_LOCUS1092 | NAV_LOCUS2015 | A0A498SCF4 | A0A498S8T8 | Adenylosuccinate synthetase; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP. | Pribosyltran domain-containing protein. | 0.885 |
NAV_LOCUS1092 | NAV_LOCUS3731 | A0A498SCF4 | A0A498SD85 | Adenylosuccinate synthetase; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP. | Ribokinase; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway. | 0.982 |
NAV_LOCUS1092 | NAV_LOCUS3767 | A0A498SCF4 | A0A498SG87 | Adenylosuccinate synthetase; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP. | Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. | 0.894 |
NAV_LOCUS1092 | NAV_LOCUS38 | A0A498SCF4 | A0A498S5I6 | Adenylosuccinate synthetase; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP. | Uncharacterized protein. | 0.845 |
NAV_LOCUS1092 | NAV_LOCUS6099 | A0A498SCF4 | A0A498SGH1 | Adenylosuccinate synthetase; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP. | ADSL_C domain-containing protein. | 0.999 |
NAV_LOCUS1092 | NAV_LOCUS6140 | A0A498SCF4 | A0A498SQB5 | Adenylosuccinate synthetase; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP. | OMPdecase domain-containing protein. | 0.830 |
NAV_LOCUS1092 | NAV_LOCUS625 | A0A498SCF4 | A0A498S764 | Adenylosuccinate synthetase; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP. | GMP reductase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides. | 0.996 |
NAV_LOCUS1092 | NAV_LOCUS7019 | A0A498SCF4 | A0A498SMB9 | Adenylosuccinate synthetase; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP. | Succinate--CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and specificity for either ATP or GTP is provided by different beta subunits. | 0.678 |
NAV_LOCUS1092 | NAV_LOCUS7939 | A0A498SCF4 | A0A498ST05 | Adenylosuccinate synthetase; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP. | Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. | 0.894 |
NAV_LOCUS1092 | NAV_LOCUS798 | A0A498SCF4 | A0A498RYR9 | Adenylosuccinate synthetase; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP. | Uncharacterized protein. | 0.950 |
NAV_LOCUS2015 | NAV_LOCUS1092 | A0A498S8T8 | A0A498SCF4 | Pribosyltran domain-containing protein. | Adenylosuccinate synthetase; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP. | 0.885 |
NAV_LOCUS2015 | NAV_LOCUS3731 | A0A498S8T8 | A0A498SD85 | Pribosyltran domain-containing protein. | Ribokinase; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway. | 0.979 |
NAV_LOCUS2015 | NAV_LOCUS3767 | A0A498S8T8 | A0A498SG87 | Pribosyltran domain-containing protein. | Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. | 0.533 |
NAV_LOCUS2015 | NAV_LOCUS38 | A0A498S8T8 | A0A498S5I6 | Pribosyltran domain-containing protein. | Uncharacterized protein. | 0.994 |
NAV_LOCUS2015 | NAV_LOCUS6099 | A0A498S8T8 | A0A498SGH1 | Pribosyltran domain-containing protein. | ADSL_C domain-containing protein. | 0.983 |
NAV_LOCUS2015 | NAV_LOCUS6140 | A0A498S8T8 | A0A498SQB5 | Pribosyltran domain-containing protein. | OMPdecase domain-containing protein. | 0.940 |
NAV_LOCUS2015 | NAV_LOCUS625 | A0A498S8T8 | A0A498S764 | Pribosyltran domain-containing protein. | GMP reductase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides. | 0.969 |
NAV_LOCUS2015 | NAV_LOCUS7019 | A0A498S8T8 | A0A498SMB9 | Pribosyltran domain-containing protein. | Succinate--CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and specificity for either ATP or GTP is provided by different beta subunits. | 0.406 |
NAV_LOCUS2015 | NAV_LOCUS7939 | A0A498S8T8 | A0A498ST05 | Pribosyltran domain-containing protein. | Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. | 0.533 |
NAV_LOCUS3731 | NAV_LOCUS1092 | A0A498SD85 | A0A498SCF4 | Ribokinase; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway. | Adenylosuccinate synthetase; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP. | 0.982 |