STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NAV_LOCUS8021CAAX prenyl protease; Proteolytically removes the C-terminal three residues of farnesylated proteins; Belongs to the peptidase M48A family. (500 aa)    
Predicted Functional Partners:
NAV_LOCUS5679
Uncharacterized protein.
    
 0.981
NAV_LOCUS764
Protein farnesyltransferase subunit beta; Catalyzes the transfer of a farnesyl moiety from farnesyl diphosphate to a cysteine at the fourth position from the C-terminus of several proteins. The beta subunit is responsible for peptide-binding.
     
 0.947
NAV_LOCUS6741
Uncharacterized protein.
     
 0.946
NAV_LOCUS3744
GrpE protein homolog; Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner; Belongs to the GrpE family.
  
  
 0.881
NAV_LOCUS1771
Uncharacterized protein; Belongs to the GroES chaperonin family.
  
  
 0.852
NAV_LOCUS5286
Nas2_N domain-containing protein.
  
  
 0.818
NAV_LOCUS2695
Major sperm protein; Central component in molecular interactions underlying sperm crawling. Forms an extensive filament system that extends from sperm villipoda, along the leading edge of the pseudopod.
  
 
 0.804
NAV_LOCUS5929
Plug_translocon domain-containing protein; Belongs to the membrane-bound acyltransferase family.
  
 
 0.796
NAV_LOCUS1197
GTP_cyclohydroI domain-containing protein.
  
  
 0.785
NAV_LOCUS369
Lon protease homolog, mitochondrial; ATP-dependent serine protease that mediates the selective degradation of misfolded, unassembled or oxidatively damaged polypeptides as well as certain short-lived regulatory proteins in the mitochondrial matrix. May also have a chaperone function in the assembly of inner membrane protein complexes. Participates in the regulation of mitochondrial gene expression and in the maintenance of the integrity of the mitochondrial genome. Binds to mitochondrial DNA in a site-specific manner; Belongs to the peptidase S16 family.
   
 
 0.755
Your Current Organism:
Acanthocheilonema viteae
NCBI taxonomy Id: 6277
Other names: A. viteae, Dipetalonema viteae
Server load: low (28%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.