STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NAV_LOCUS6860Uncharacterized protein. (451 aa)    
Predicted Functional Partners:
NAV_LOCUS4935
ATP-dependent Clp protease proteolytic subunit.
 0.997
NAV_LOCUS369
Lon protease homolog, mitochondrial; ATP-dependent serine protease that mediates the selective degradation of misfolded, unassembled or oxidatively damaged polypeptides as well as certain short-lived regulatory proteins in the mitochondrial matrix. May also have a chaperone function in the assembly of inner membrane protein complexes. Participates in the regulation of mitochondrial gene expression and in the maintenance of the integrity of the mitochondrial genome. Binds to mitochondrial DNA in a site-specific manner; Belongs to the peptidase S16 family.
  
 
 0.806
NAV_LOCUS3002
Peptide-methionine (R)-S-oxide reductase; Methionine-sulfoxide reductase that specifically reduces methionine (R)-sulfoxide back to methionine. While in many cases methionine oxidation is the result of random oxidation following oxidative stress, methionine oxidation is also a post-translational modification that takes place on specific residues.
  
 
 0.687
NAV_LOCUS7751
ATPase_AAA_core domain-containing protein.
  
  
 0.672
NAV_LOCUS8655
S-adenosylmethionine synthase; Catalyzes the formation of S-adenosylmethionine from methionine and ATP.
   
 
 0.669
NAV_LOCUS2908
AAA domain-containing protein.
  
  
 0.668
NAV_LOCUS3744
GrpE protein homolog; Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner; Belongs to the GrpE family.
  
 
 0.645
NAV_LOCUS1092
Adenylosuccinate synthetase; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP.
  
  
 0.630
NAV_LOCUS3005
Uncharacterized protein; Belongs to the AAA ATPase family.
  
  
 0.626
NAV_LOCUS2513
Uncharacterized protein.
  
  
 0.616
Your Current Organism:
Acanthocheilonema viteae
NCBI taxonomy Id: 6277
Other names: A. viteae, Dipetalonema viteae
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.