STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NAV_LOCUS8493Uncharacterized protein. (303 aa)    
Predicted Functional Partners:
NAV_LOCUS2514
ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily.
   
 0.993
NAV_LOCUS3221
Uncharacterized protein.
   
 0.992
NAV_LOCUS7822
Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage.
   
 0.992
NAV_LOCUS5002
Uncharacterized protein; Belongs to the PI3/PI4-kinase family.
   
 0.987
NAV_LOCUS4073
Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.
   
 0.985
NAV_LOCUS4232
DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family.
    
 0.983
NAV_LOCUS1977
DUF1767 domain-containing protein.
    
 0.982
NAV_LOCUS775
PWI domain-containing protein.
   
 0.979
NAV_LOCUS980
DNA primase; Belongs to the eukaryotic-type primase small subunit family.
   
 0.975
NAV_LOCUS3446
H15 domain-containing protein.
   
 0.972
Your Current Organism:
Acanthocheilonema viteae
NCBI taxonomy Id: 6277
Other names: A. viteae, Dipetalonema viteae
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.