STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Bm1_10605Bm4914. (412 aa)    
Predicted Functional Partners:
Bm1_29495
BMA-WSP-1.
    
 
 0.870
Bm1_37065
BMA-SEL-5, isoform c; BMA-SEL-5, isoform e.
    
 
 0.816
bma-cap-2
F-actin-capping protein subunit beta; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.
   
 0.791
Bma-plst-1
BMA-PLST-1.
   
 
 0.780
Bm1_26610
Actin-related protein 2; ATP-binding component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF). The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility. Seems to contact the pointed end of the daughter actin filament.
   
 
 0.752
Bm1_00810
BMA-AMPH-1.
   
 
 0.742
A0A5S6PD68
Uncharacterized protein.
    
 
 0.734
bma-act-5
Actin; BMA-ACT-5.
   
 
 0.721
ACT_BRUMA
Actin; Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells; Belongs to the actin family.
   
 
 0.721
Prof
Profilin; Belongs to the profilin family.
   
  
 0.665
Your Current Organism:
Brugia malayi
NCBI taxonomy Id: 6279
Other names: B. malayi, agent of lymphatic filariasis
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.