STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Bm7635Bm7635. (458 aa)    
Predicted Functional Partners:
Bma-swsn-4
BMA-SWSN-4.
   
 0.997
bma-swsn-1
BMA-SWSN-1, isoform a; BMA-SWSN-1, isoform b.
    
 0.997
bma-swsn-6
BMA-SWSN-6; Belongs to the actin family.
   
 0.991
Bm1_07975
Bm10215.
   
 0.841
Bm1_49390
Bm6320.
   
 0.841
Bm9746
Bm9746.
   
 0.841
Bm1898
Bm1898.
   
 
 0.835
A0A5S6PG44
Bm1898.
   
 
 0.835
bma-cfi-1
Bm7813, isoform a; Bm7813, isoform c.
   
 
 0.833
Bma-his-56
Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
    
  0.826
Your Current Organism:
Brugia malayi
NCBI taxonomy Id: 6279
Other names: B. malayi, agent of lymphatic filariasis
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.